202737-42-6 Usage
Description
1-(4-NITROPHENYL)CYCLOBUTANECARBOXYLIC ACID is a chemical compound with the molecular formula C11H9NO4, derived from cyclobutanecarboxylic acid with a nitrophenyl substituent at the 1-position. It is a yellow solid at room temperature, insoluble in water, but soluble in organic solvents. The nitro group on the phenyl ring allows for various chemical reactions, making it a versatile building block in organic chemistry. Its properties make it a valuable compound in the field of medicinal and pharmaceutical chemistry.
Uses
Used in Pharmaceutical Synthesis:
1-(4-NITROPHENYL)CYCLOBUTANECARBOXYLIC ACID is used as an intermediate for the synthesis of pharmaceuticals and other organic compounds. Its unique structure and reactivity contribute to the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, 1-(4-NITROPHENYL)CYCLOBUTANECARBOXYLIC ACID is used as a versatile building block for the creation of various chemical compounds. The nitro group on the phenyl ring can participate in a range of chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
1-(4-NITROPHENYL)CYCLOBUTANECARBOXYLIC ACID is used as a key component in the development of new drugs and therapeutic agents in medicinal chemistry. Its properties and reactivity make it a promising candidate for the design and synthesis of novel pharmaceuticals with potential applications in treating various diseases and medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 202737-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,2,7,3 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 202737-42:
(8*2)+(7*0)+(6*2)+(5*7)+(4*3)+(3*7)+(2*4)+(1*2)=106
106 % 10 = 6
So 202737-42-6 is a valid CAS Registry Number.
202737-42-6Relevant articles and documents
Thermal Decomposition of
Wolf, Richard A.,Trocino, Richard J.,Rozich, William R.,Sabeta, Isidore C.,Ordway Jr., Richard J.
, p. 3814 - 3820 (1998)
A series of tert-butyl 1-arylcycloalkyl peresters was prepared, and the rate constants for the peresters' thermal decomposition were measured at several temperatures. The decomposition rates and aryl-substituent effects on the decomposition rates for the three series of peresters are remarkably similar to each other and to the acyclic α,α-dimethylbenzyl analogue previously investigated. The magnitude of the activation parameters for the rates of thermolysis of the alicyclic peresters and the solvent viscosity effects on these rates suggest that the 1-arylcyclobutyl (2), -cyclopentyl (3), and -cyclohexyl (4) peresters undergo thermal decomposition primarily by the concerted, two-bond-cleavage mechanism and that the 1-arylcyclopropyl peresters (1) undergo thermolysis primarily by the stepwise mechanism.
NOVEL SUBSTITUTED CYCLOBUTYLBENZENE COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS
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, (2019/05/02)
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.
PROCESS OF PREPARING 3-(3-(4-(1-AMINOCYCLOBUTYL)PHENYL)-5-PHENYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PYRIDIN-2-AMINE
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Paragraph 0167; 0168, (2015/11/03)
The present invention is directed to a processes for the synthesis of 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine:
