203258-20-2

Basic information

• Product Name: Carbamic acid, [[[(1,1-dimethylethoxy)carbonyl]amino]-1-piperazinylmethylene]-, 1,1-dimethylethyl ester
• CAS NO: 203258-20-2
• Molecular Formula: C15H28N4O4
• Molecular Weight: 328.412
• Mol File: 203258-20-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[[(1,1-dimethylethoxy)carbonyl]amino]-1-piperazinylmethylene]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[[(1,1-dimethylethoxy)carbonyl]amino]-1-piperazinylmethylene]-, 1,1-dimethylethyl ester(203258-20-2)
• EPA Substance Registry System: Carbamic acid, [[[(1,1-dimethylethoxy)carbonyl]amino]-1-piperazinylmethylene]-, 1,1-dimethylethyl ester(203258-20-2)

Safety Data

• Hazardous Substances Data: 203258-20-2(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 322474-21-5 N,N'-bis-Boc-S-methyl-isothiourea 
• 207857-15-6 1,3-di(tert-butyloxycarbonyl)-2-(trifluoromethylsulfonyl)guanidine 

Downstream Products

• 1379574-05-6 C₂₄H₃₆N₄O₆ 
• 215050-21-8 3-{4-[4-(tert-butoxycarbonylamino-tert-butoxycarbonylimino-methyl)-piperazin-1-yl]-3-nitro-benzoylamino}-2-(naphthalene-2-sulfonylamino)-propionic acid tert-butyl ester 
• 215050-20-7 2-benzenesulfonylamino-3-{4-[4-(tert-butoxycarbonylamino-tert-butoxycarbonylimino-methyl)-piperazin-1-yl]-3-nitro-benzoylamino}-propionic acid tert-butyl ester 

Relevant articles and documents

SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES

The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the substituents are as defined in the description). The compounds of the general formula (I) are inhibitors of factor XIa, and are useful in the prevention of and/or therapy for thromboembolic diseases.

Tobramycin analogues with C-5 aminoalkyl ether chains intended to mimic rings III and IV of paromomycin

Based on available X-ray structural and modeling data, a series of tobramycin derivatives with C-5 ether chains bearing basic groups were synthesized. These were intended to be hybrid molecules that combine features of tobramycin and paromomycin. Their binding to ribosomes and their antibacterial activity were determined. The 5-O-(2-guanidylethyl) ether of tobramycin (9g) was the most active analogue in the series.

Solution phase combinatorial chemistry. Discovery of 13- and 15-membered polyazapyridinocyclophane libraries with antibacterial activity

A solution phase simultaneous addition of functionalities (SPSAF) combinatorial approach was utilized to synthesize 40 polyazacyclophane libraries (total complexity of 4275). Eighteen different functionality sets, utilizing 42 functionalities, were design