322474-21-5Relevant articles and documents
Leonurine derivative and application thereof in preparing medicine for preventing or treating ischemic cerebrovascular diseases
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Paragraph 0029-0031, (2021/03/30)
The invention provides a leonurine derivative and application of the leonurine derivative in preparation of a medicine for preventing or treating ischemic cerebrovascular diseases. The leonurine derivative has a structure as shown in a general formula (I), wherein X is selected from O or NH; Y is selected from any one of natural amino acid, substituted amino acid or amino alcohol; Z is selected from H, proline and any substituted proline. Pharmacological experiments prove that the leonurine derivative provided by the invention has the effects of neuroprotection, cerebral infarction area reduction and animal neurobehavioral scoring, and is good in safety, so that the leonurine derivative has important significance for developing novel medicines for preventing or treating ischemic cerebrovascular diseases.
Synthesis of Nω,Νω–di-Boc-3-guanidylpropanal - An Important Reagent for Synthesis of Aza-Arg Precursors
Mastitski, Anton,Troska, Alla,J?rv, Jaak
, p. 472 - 478 (2021/09/18)
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ANALGESIC AND ANTI-ADDICTIVE COMPOSITIONS FOR TREATMENT OF CHRONIC PAIN AND OPIOID ADDICTION
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Page/Page column 28-30, (2020/06/10)
The invention provides a compound of formula I and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments t