2043-57-4

Basic information

• Product Name: 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane
• Synonyms: 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-8-iodo-octan;1,1,2,2-Tetrahydroperfluorooctyliodide;2-Perfluorohexyl-1-iodoethane;2-(PERFLUOROHEXYL)ETHYL IODIDE;3,3,4,4,5,5,6,6,7,7,8,8,8-TRIDECAFLUORO-1-IODOOCTANE;3,3,4,4,5,5,6,6,7,7,8,8,8-TRIDECAFLUOROOCTYL IODIDE;1,1,1,2,2,3,3,4,4,5,5,6,6-TRIDECAFLUORO-8-IODOOCTANE;1-IODO-1H,1H,2H,2H-PERFLUOROOCTANE
• CAS NO: 2043-57-4
• Molecular Formula: C₈H₄F₁₃I
• Molecular Weight: 474
• EINECS: 218-056-1
• Mol File: 2043-57-4.mol
• Article Data: 15

Chemical Properties

• Melting Point: 21 °C
• Boiling Point: 92 °C45 mm Hg(lit.)
• Flash Point: 177 °F
• Appearance: Clear/Liquid
• Density: 1.934 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.29mmHg at 25°C
• Refractive Index: n20/D 1.359(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: Chloroform (Soluble), Methanol (Slightly)
• Water Solubility: insoluble
• Sensitive: Light Sensitive
• Stability: Volatile
• BRN: 1887105
• CAS DataBase Reference: 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane(2043-57-4)
• EPA Substance Registry System: 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane(2043-57-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 8
• TSCA: T
• HazardClass: IRRITANT-HARMFUL
• Hazardous Substances Data: 2043-57-4(Hazardous Substances Data)

Usage

Description

1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane, also known as Perfluorohexylethyl Iodide, is a polyfluorinated iodine alkane (PFI) compound. It is characterized by its unique structure with multiple fluorine and iodine atoms attached to an octane backbone. 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane is a clear liquid and serves as an important intermediate in the synthesis of various organic fluoride products.

Uses

Used in Organic Synthesis:
1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane is used as an intermediate in the synthesis of organic fluoride products for various applications. Its unique structure allows for the formation of a wide range of fluorinated compounds with diverse properties and potential uses in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane is used as a building block for the development of new drugs with improved properties. Its fluorinated nature can enhance the stability, solubility, and bioavailability of drug molecules, leading to more effective therapeutic agents.
Used in Chemical Research:
1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane is also used in chemical research as a model compound to study the properties and behavior of polyfluorinated compounds. This can help in understanding the fundamental aspects of fluorine chemistry and its applications in various fields.
Used in Environmental Applications:
Due to its potential estrogenic effects, 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane can be used in environmental studies to understand the impact of polyfluorinated compounds on the endocrine system and develop strategies for mitigating their effects on ecosystems.

InChI:InChI=1/C8H4F13I/c9-3(10,1-2-22)4(11,12)5(13,14)6(15,16)7(17,18)8(19,20)21/h1-2H2

Upstream product

• 74-85-1 ethene 
• 355-43-1 n-perfluorohexyl iodide 
• 74-95-3 1,1-dibromomethane 
• 647-42-7 1H,1H,2H,2H-tridecafluoro-n-octanol 
• 507-63-1 1-iodoheptadecafluorooctane 
• 307-60-8 1-iodoperfluorododecane 
• 423-62-1 1-Iodo-perfluorodecane 

Downstream Products

• 26650-09-9 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl thiocyanate 
• 25291-17-2 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene 
• 647-42-7 1H,1H,2H,2H-tridecafluoro-n-octanol 
• 78522-69-7 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl trifluoromethanesulfonate 
• 27854-30-4 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluorononanoic acid 
• 80793-17-5 (perfluoro-n-hexyl)ethane 
• 34451-26-8 2-perfluorohexylethanethiol 
• 76598-01-1 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl magnesium iodide 
• 103249-38-3 tris(1H,1H,2H,2H-perfluorooctyl)phosphine 
• 51066-74-1 dimethylamine hydriodide 
• 87851-83-0 benzyl(F-hexyl-2 ethyl) sulfure 
• 94190-73-5 (1H,1H,2H,2H-perfluorooctyl)triphenylphosphonium iodide 
• 7060-52-8 1-(1-pyrrolin-2-yl)-2-pyrrolidinone 

Relevant articles and documents

Novel fluorinated amphiphilic cyclodextrin derivatives: Synthesis of mono-, di- and heptakis-(6-deoxy-6-perfluoroalkylthio)-β-cyclodextrins

A new series of fluorinated amphiphilic β-cyclodextrin derivatives has been synthesized. The strategy is based on the modification of the C-6 position of the mono-6-deoxy-6A-para-tolylsulfonyl, di-6A, 6D-deoxy-6A, 6D-(para-tolylsulfonyl) and heptakis-(6-deoxy-6-iodo)-β-cyclodextrin precursors. The synthesis lead to mono-perfluoroalkylthio-, di-perfluoroalkylthio- and heptakis-perfluoroalkylthio-β-cyclodextrin in excellent yields (90-99%).

Synthesis of perfluoroalkyl-containing multifunctional groups compounds for textile finishing

A new kind of perfluoroalkyl-containing multifunctional groups compound was designed. Treatment of 1H.1H.2H.2H-perfluorooctyltri- chlorosilane (4) with allylmagnesium bromide provided key intermediate 1H,1H,2H,2H-perfluorooctyltriallylsilane (2). Hydroboration followed by oxidation, epoxidation and dihydroxylation of 2 gave perfluoroalkyl-containing multifunctional groups compound 1a, 1b and 1c, respectively.

Environmentally friendly preparation method of fluorine-containing acrylate

The invention relates to the technical field of preparation of new fluorine-containing materials, particularly to an environmentally friendly preparation method of fluorine-containing acrylate. The environmentally friendly preparation method comprises: carrying out a reaction on short-chain perfluoroiodoalkane and ethylene, separating, and purifying to obtain perfluoroalkylethyl iodide; carrying out hydrolysis on the perfluoroalkylethyl iodide, separating, and purifying to obtain perfluoroalkylethanol; and carrying out a reaction on the perfluoroalkylethanol and acrylic acid, separating, and purifying to obtain the product. According to the present invention, the perfluorooctyl-free product is synthesized, the potential risk of PFOA production cannot exist, and the obtained product is theenvironmentally friendly product, and meets the national industrial policy; the preparation method is simple, and is suitable for industrial production; and the reaction conversion rate is high, and the purity of the intermediate product is high, such that the subsequent reaction is easily performed, the yield is easily increased, and the cost is reduced.

Crosslinking of fluoroelastomers by "click" azide-nitrile cycloaddition

A fluoroelastomer that bears pendant nitrile groups is crosslinked with a telechelic bis-azido fluorinated curing agent by "click" azide-nitrile cycloaddition. Thermogravimetric analyses of the resulting press cured films reveal an improvement by 20 C of the thermal degradation profile under air, compared to that of the corresponding uncured fluoroelastomer.