307-60-8

Basic information

• Product Name: Perfluorododecyl iodide
• Synonyms: Dodecane, 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12-pentacosafluoro-12-iodo-;dodecane,1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12-pentacosafluo;ro-12-iodo-;1-IODOPERFLUORODODECANE;PERFLUORODODECYL IODIDE;1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12-pentacosafluoro-12-iodododecane;pentacosafluoro-1-iodododecane;Perfluorododecyl iodide 97%
• CAS NO: 307-60-8
• Molecular Formula: C₁₂F₂₅I
• Molecular Weight: 745.99
• EINECS: 206-205-3
• Mol File: 307-60-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 95-98 °C(lit.)
• Boiling Point: 108-110 °C18 mm Hg(lit.)
• Flash Point: 110.8°C
• Appearance: /
• Density: 1.9588 (estimate)
• Vapor Pressure: 0.126mmHg at 25°C
• Refractive Index: 1.312
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• BRN: 1718343
• CAS DataBase Reference: Perfluorododecyl iodide(CAS DataBase Reference)
• NIST Chemistry Reference: Perfluorododecyl iodide(307-60-8)
• EPA Substance Registry System: Perfluorododecyl iodide(307-60-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 8
• TSCA: T
• HazardClass: IRRITANT
• Hazardous Substances Data: 307-60-8(Hazardous Substances Data)

Usage

Description

Perfluorododecyl iodide, also known as Pentacosafluoro-1-iodododecane, is a chemical compound characterized by its yellow waxy chunks appearance. It is a perfluorinated alkyl iodide, which means that all the hydrogen atoms in the molecule have been replaced by fluorine atoms. This unique property endows it with exceptional chemical stability and resistance to various environmental conditions.

Uses

1. Used in Biosensing Applications:
Perfluorododecyl iodide is used as a self-assembling material on a silicon nitride surface for biosensing applications. The self-assembly property of this compound allows for the creation of highly ordered and stable structures, which are crucial for the accurate detection and analysis of biological molecules.
2. Used in E-screen Assay:
Perfluorododecyl iodide is utilized in the E-screen assay to investigate the estrogenic activities of polyfluorinated iodine alkanes in MCF-7 cells. This application is significant for understanding the potential endocrine-disrupting effects of these compounds and their impact on human health and the environment.

InChI:InChI=1/C12F25I/c13-1(14,3(17,18)5(21,22)7(25,26)9(29,30)11(33,34)35)2(15,16)4(19,20)6(23,24)8(27,28)10(31,32)12(36,37)38

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 354-64-3 Pentafluoroethyl iodide 
• 423-39-2 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane 

Downstream Products

• 307-59-5 perfluorododecane 
• 3042-22-6 2-phenyl-1H-pyrrole 
• 141246-55-1 2-perfluorododecanoylpyrrole 
• 305344-21-2 Dimethyl 5-(7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-pentacosafluoro-n-octadecyloxy)isophthalate 
• 2043-57-4 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane 
• 2043-53-0 2-(n-perfluorooctyl)ethyl iodide 

Relevant articles and documents

PROCESS FOR PRODUCING FLUOROALKYL IODIDE TELOMER

A novel process for producing a fluoroalkyl iodide telomer is provided, which is able to obtain a fluoroalkyl iodide telomer having a desired chain length, efficiently. A fluoroalkyl iodide represented by the general formula RfI (wherein Rf is a C1-10 fluoroalkyl group) and tetrafluoroethylene are used as a telogen and a taxogen, respectively. These compounds are supplied to a distillation apparatus. In a reaction zone located in an intermediate part of the distillation apparatus, the compounds are subjected to a telomerization reaction in the presence of a metal catalyst with heating to generate a fluoroalkyl iodide telomer represented by the general formula Rf(CF2CF2)nI (wherein Rf is the same as defined above and n is an integer of 1-4). Thereafter, a fraction comprising the fluoroalkyl iodide telomer is separated by distillation.

METHOD FOR CONTINUOUS PRODUCTION OF A PERFLUOROALKYL IODIDE TELOMER

The present invention relates to a process for continuously producing a perfluoroalkyl iodide represented by the general formula Rf(CF2CF2)nI, wherein Rf is a C1-6 perfluoroalkyl and n is an integer from 1 to 4, the method comprising continuously supplying a perfluoroalkyl iodide as a telogen represented by the general formula RfI, wherein Rf is as defined above, and tetrafluoroethylene as a taxogen to a tubular reactor packed with a metal catalyst comprising a powdery spherical metal or a sintered metal; and conducting telomerization at a temperature of 60 to 160°C under a pressure of 0.1 to 5 MPa (gauge pressure). According to the present invention, medium-chain perfluoroalkyl iodides can be continuously and efficiently produced with little generation of impurities, such as hydrogen-containing organic compounds and the like.