307-59-5

Basic information

• Product Name: PERFLUORODODECANE
• Synonyms: dodecane,hexacosafluoro-;hexacosafluorododecane;PERFLUORODODECANE;Perfluoro-n-dodecane;Perfluorododecane 97%;Perfluorododecane97%;n-Perfluorododecane;n-Pefluorododecane
• CAS NO: 307-59-5
• Molecular Formula: C₁₂F₂₆
• Molecular Weight: 638.09
• EINECS: 206-204-8
• Mol File: 307-59-5.mol
• Article Data: 12

Chemical Properties

• Melting Point: 75 °C
• Boiling Point: 178°C
• Flash Point: 178°C
• Appearance: /
• Density: >1.5
• Vapor Pressure: 0.693mmHg at 25°C
• Refractive Index: 1.2830 (estimate)
• BRN: 1811139
• CAS DataBase Reference: PERFLUORODODECANE(CAS DataBase Reference)
• NIST Chemistry Reference: PERFLUORODODECANE(307-59-5)
• EPA Substance Registry System: PERFLUORODODECANE(307-59-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 307-59-5(Hazardous Substances Data)

Usage

General Description

Perfluorododecane is a fluorocarbon compound with the chemical formula C12F26. It is a colorless and odorless liquid and belongs to the class of perfluoroalkanes. Perfluorododecane is characterized by its unique properties, including high chemical and thermal stability, as well as low surface tension and high solubility in organic solvents. It is primarily used as a lubricant, surfactant, and solvent in various industrial applications, such as in the production of electronic components, coatings, and in the pharmaceutical and cosmetic industries. Additionally, perfluorododecane is utilized in research and development for its ability to create stable emulsions and foams, as well as its potential as a contrast agent in medical imaging. Its inertness and non-toxic nature also make it suitable for use in biological and medical applications.

InChI:InChI=1/C12F26/c13-1(14,3(17,18)5(21,22)7(25,26)9(29,30)11(33,34)35)2(15,16)4(19,20)6(23,24)8(27,28)10(31,32)12(36,37)38

Upstream product

• 112-40-3 dodecane 
• 307-60-8 1-iodoperfluorododecane 
• 6294-31-1 hexyl sulfide 
• 355-43-1 n-perfluorohexyl iodide 
• 565-80-0 2,4-dimethylpentan-3-one 
• 96-49-1 [1,3]-dioxolan-2-one 
• 507-63-1 1-iodoheptadecafluorooctane 
• 100-47-0 benzonitrile 
• 21049-36-5 tridecafluoroheptanoic potassium salt 
• 105-58-8 Diethyl carbonate 
• 74-95-3 1,1-dibromomethane 
• 307-35-7 perfluorooctyl sulfofluorure 
• 107-18-6 allyl alcohol 
• 115-19-5 2-methyl-but-3-yn-2-ol 

Relevant articles and documents

Nonmetallic Wurtz coupling reaction of perfluorohexyl iodide

It is shown for the first time that the Wurtz reaction can be realized by the action of an organic substance (triphenylphosphine) on an alkyl halide (perfluoroalkyl iodide) without the use of metals. It was found that when trying to prepare the bis(3,3′-aminophenyl)(fluoroalkyl)phosphine oxide by four-step synthesis, in the first stage of the reaction of perfluoro-1-iodohexane with triphenylphosphine does not proceed towards the formation of an intermediate quaternary phosphonium salt. Instead, the carbon chain of perfluoroalkyl iodide dimerizes to form perfluorododecane – Wurtz reaction product. We have proposed a new pathway for homocoupling of perfluoroalkylhalides into even-numbered perfluoroalkanes.

An improved procedure for the synthesis of perfluoroalkylacetylenes

A new and easy way to synthesize acetylene compounds is proposed. This synthesis is improved by including in one-pot, three reactions in a single step, with good yields. The reactants are commonly used compounds.

Reaction of Perfluoroalkyl Iodides with Lithium Salt of 5-Nitro-3-tert-butyl-1,3-tetrahydrooxazine

Reaction of perfluoroalkyl iodides C6F13I and C8H17I with lithium salt of 5-nitro-3-tert-butyl-1,3-tetrahydrooxazine in DMSO at 20°C for 24 h in an argon atmosphere gives 5-nitro-5-perfluoroalkyl-3-tert-butyl-1,3-tetrahydrooxazines (yield 66-75%), 5,5′-bis(5-nitro-3-tert-butyltetrahydro-1,3-oxazinyl) (yield 3-5%), and, respectively, perfluorododecane and perfluorohexadecane. The reaction is accelerated under UV irradiation.