205116-75-2

Basic information

• Product Name: 2-(2,9,9-TriMethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)-pyrrolidine
• Synonyms: 2-(2,9,9-TriMethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)-pyrrolidine;2-(3a,5,5-TriMethylhexahydro-4,6-Methanobenzo[d][1,3,2]dioxaborol-2-yl)pyrrolidine;2-(2,9,9-TriMethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)-pyrrolidine 1-Pyrrolidinecarboxylic acid, 2-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimeth;NT 0188;2-[(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester;(R)-2-((3AS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)pyr;tert-butyl 2-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 2-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-, 1,1-dimethylethyl ester
• CAS NO: 205116-75-2
• Molecular Formula: C₁₉H₃₂BNO₄
• Molecular Weight: 249.15686
• Mol File: 205116-75-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(2,9,9-TriMethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,9,9-TriMethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)-pyrrolidine(205116-75-2)
• EPA Substance Registry System: 2-(2,9,9-TriMethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)-pyrrolidine(205116-75-2)

Safety Data

• Hazardous Substances Data: 205116-75-2(Hazardous Substances Data)

Usage

General Description

2-(2,9,9-TriMethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.02,6]dec-4-yl)-pyrrolidine is a chemical compound with a complex molecular structure. It contains a boron atom and a tricyclic ring system, as well as a pyrrolidine ring. The compound has three methyl groups attached to the boron atom, giving it a bulky and sterically hindered structure. This chemical may have potential applications in organic synthesis or medicinal chemistry due to its unique structure and properties. Further research and study into its potential uses and reactivity are needed to fully understand the implications of this compound.

Upstream product

• 86953-79-9 tert-butyl pyrrolidine-1-carboxylate 

Downstream Products

• 149716-72-3 (RS)-proline boronic acid-(1S,2S,3R,5S)-(+)-2,3-pinanediol ester hydrochloride 
• 149716-72-3 (1S,2S,3R,5S)-pinanediol L-proline boronate hydrochloride 
• 149716-72-3 L-proline boric acid-(1S,2S,3R,5S)-(+)-2,3-pinanediol ester hydrochloride 

Relevant articles and documents

Proline boric acid compound and preparation method and applications thereof

The invention provides a compound whose structure is shown as a formula (I) or a salt thereof. The compound is a proline boric acid proteasome inhibitor compound, and has good proteasome inhibitory activity and excellent druggability. The structural formula of the compound is shown as the formula (I).

A (-)-sparteine-directed highly enantioselective synthesis of boroproline. Solid- and solution-state structure and properties

(Chemical Equation Presented) A two-step, direct asymmetric synthesis of the trifluoroacetate ammonium salt of boroproline is reported. (-)-Sparteine-mediated lithiation of N-Boc-pyrrolidine afforded N-Boc-aminoboronic acid in good yield and enantioselectivity as determined by HPLC (pinanediol ester). Deprotection using TFA yielded the ammonium salt; full characterization data are presented, and the structure in aqueous solution and the occurrence of a B-N species are discussed.