205676-84-2

Basic information

• Product Name: (TERT-BUTOXY)-N-METHYL-N-[6-METHYL-(2-PYRIDINYL)]CARBOXAMIDE
• Synonyms: TERT-BUTYL METHYL(6-METHYLPYRIDIN-2-YL)CARBAMATE;(TERT-BUTOXY)-N-METHYL-N-[6-METHYL-(2-PYRIDINYL)]CARBOXAMIDE;(6-METHYL-PYRIDIN-2-YL)-CARBAMICACIDTERT-BUTYLESTER
• CAS NO: 205676-84-2
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.28
• Mol File: 205676-84-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 261.4°C at 760 mmHg
• Flash Point: 111.9°C
• Appearance: /
• Density: 1.108g/cm³
• Vapor Pressure: 0.0116mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: 2-8°C
• PKA: 4.18±0.10(Predicted)
• CAS DataBase Reference: (TERT-BUTOXY)-N-METHYL-N-[6-METHYL-(2-PYRIDINYL)]CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (TERT-BUTOXY)-N-METHYL-N-[6-METHYL-(2-PYRIDINYL)]CARBOXAMIDE(205676-84-2)
• EPA Substance Registry System: (TERT-BUTOXY)-N-METHYL-N-[6-METHYL-(2-PYRIDINYL)]CARBOXAMIDE(205676-84-2)

Safety Data

• Hazardous Substances Data: 205676-84-2(Hazardous Substances Data)

Usage

General Description

"(Tert-butoxy)-N-methyl-N-[6-methyl-(2-pyridinyl)]carboxamide is a chemical compound which belongs to the category of aromatic homomonocyclic compounds. This chemical compound is mostly used in scientific laboratories and academic research. The structure of this compound includes an aromatic ring, methyl groups, a carboxamide group and an alkoxy group. While it's not widely known for a specific use as compared to other compounds, it may be utilized in the production of various pharmaceuticals or as a reagent in chemical reactions. The name can be broken down into components which describe its structure: "Tert-butoxy" represents that it has a tertiary butyl group with an oxygen, "N-methyl" indicates a nitrogen attached to a methyl group, and "N-[6-methyl-(2-pyridinyl)]carboxamide" shows that it has a carboxamide group attached to a nitrogen which is also bonded to a 6-methyl-2-pyridinyl.

InChI:InChI=1/C11H16N2O2/c1-8-6-5-7-9(12-8)13-10(14)15-11(2,3)4/h5-7H,1-4H3,(H,12,13,14)

Upstream product

• 90101-22-7 2-(tert-butoxycarbonylamino)-6-picoline 
• 74-88-4 methyl iodide 
• 1824-81-3 2-Amino-6-methylpyridine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 78782-17-9 4,4,5,5-tetramethyl-2-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-1,3,2-dioxaborolane 

Downstream Products

• 205676-87-5 2-methylamino-6-(2-hydroxyethyl)pyridine 
• 205676-86-4 ethyl 2-[6-(methylamino)-2-pyridyl]acetate 
• 474658-52-1 [6-(2-{3-[1,1-bis(methylethyl)-2-methyl-1-silapropoxy]phenoxy}ethyl)(2-pyridyl)]methylamine 
• 474658-53-2 ethyl 5-(3-{2-[6-(methylamino)(2-pyridyl)]ethoxy}phenoxy)-4-oxopentanoate 
• 205678-31-5 (4S)-2,3,4,5-tetrahydro-8-[2-[6-(methylamino)-2-pyridinyl]ethoxy]-3-oxo-2-(2,2,2-trifluoroethyl)-1H-2-benzazepine-4-acetic acid 
• 1292954-98-3 C₂₅H₃₆N₄O₅ 
• 959991-22-1 methyl O-({6-[(tert-butoxycarbonyl)(methyl)amino]pyridin-2-yl}methyl)-N-(2,6-dichlorobenzoyl)-L-tyrosinate 

Relevant articles and documents

Transition-Metal-Free Regioselective Alkylation of Pyridine N-Oxides Using 1,1-Diborylalkanes as Alkylating Reagents

Reported herein is an unprecedented base-promoted deborylative alkylation of pyridine N-oxides using 1,1-diborylalkanes as alkyl sources. The reaction proceeds efficiently for a wide range of pyridine N-oxides and 1,1-diborylalkanes with excellent regioselectivity. The utility of the developed method is demonstrated by the sequential C?H arylation and methylation of pyridine N-oxides. The reaction also can be applied for the direct introduction of a methyl group to 9-O-methylquinine N-oxide, thus it can serve as a powerful method for late-stage functionalization.

2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases

The present invention relates to 2,6-diaminopyridine compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein and of diseases or conditions associated with amyloid-like proteins. The compoun

2,6-DIAMINOPYRIDINE COMPOUNDS SUITABLE FOR TREATING DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS OR FOR TREATING OR PREVENTING OCULAR DISEASES OR CONDITIONS ASSOCIATED WITH A PATHOLOGICAL ABNORMALITY/CHANGE IN THE TISSUE OF THE VISUAL SYSTEM

The present invention relates to 2.6-diaminopyridine compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein and of diseases or conditions associated with amyloid-like proteins. The compoun