20609-08-9

Basic information

• Product Name: 2-pyridylbenzylcarbinol
• Synonyms: 2-pyridylbenzylcarbinol;α-(2-Pyridinyl)phenethyl alcohol;α-Benzyl-2-pyridinemethanol
• CAS NO: 20609-08-9
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.25
• Mol File: 20609-08-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 371.6°Cat760mmHg
• Flash Point: 178.5°C
• Appearance: /
• Density: 1.117g/cm³
• Vapor Pressure: 3.53E-06mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 2-pyridylbenzylcarbinol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-pyridylbenzylcarbinol(20609-08-9)
• EPA Substance Registry System: 2-pyridylbenzylcarbinol(20609-08-9)

Safety Data

• Hazardous Substances Data: 20609-08-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H13NO/c15-10-8-11-5-1-2-6-12(11)13-7-3-4-9-14-13/h1-7,9,15H,8,10H2

Upstream product

• 107624-25-9 2-(benzyloxymethyl)pyridine 
• 122-78-1 phenylacetaldehyde 
• 21970-13-8 (pyridin-2-yl)magnesium bromide 
• 1121-60-4 pyridine-2-carbaldehyde 
• 128160-29-2 C₁₉H₃₄BrSb 
• 134988-30-0 benzyldibutyltelluronium bromide 
• 1589-82-8 phenylmagnesium bromide 
• 109-04-6 2-bromo-pyridine 
• 6921-34-2 benzylmagnesium chloride 
• 100-39-0 benzyl bromide 
• 4377-33-7 2-chloromethylpyridine 
• 27049-45-2 benzyl 2-pyridyl ketone 
• 100-70-9 2-Cyanopyridine 
• 108-86-1 bromobenzene 

Downstream Products

• 27049-45-2 benzyl 2-pyridyl ketone 
• 67278-01-7 2-(2,2-diphenylethyl)pyridine 
• 1609692-93-4 n-butyl 5-oxo-4-phenyl-5-(2-pyridyl)pentanoate 
• 1609692-94-5 benzyl 5-oxo-4-phenyl-5-(2-pyridyl)pentanoate 
• 1609692-95-6 5-oxo-4-phenyl-5-(2-pyridyl)pentanenitrile 
• 1609692-96-7 N-isopropyl 5-oxo-4-phenyl-5-(2-pyridyl)pentanamide 
• 1609692-97-8 C₂₁H₁₈BrNO 
• 1609692-98-9 3,6,6-trimethyl-2-phenyl-1-(2-pyridyl)hepta-1,5-dione 
• 1609693-05-1 (1-phenyl-3-formylcyclohex-3-en-1-yl)(2-pyridyl)ketone 
• 1609692-91-2 methyl 5-oxo-4-phenyl-5-(2-pyridyl)pentanoate 
• 1609692-92-3 ethyl 5-oxo-4-phenyl-5-(2-pyridyl)pentanoate 

Relevant articles and documents

Asymmetric Hydroboration of Heteroaryl Ketones by Aluminum Catalysis

A series of methyl aluminum complexes bearing chiral biphenol-type ligands were found to be highly active catalysts in the asymmetric reduction of heterocyclic ketones (S/C = 100-500, ee up to 99%). The protocol is suitable for a wide range of substrates and has a high tolerance to functional groups. The formed 2-heterocyclic-alcohols are valuable building blocks in drug discovery or can be used as ligands in asymmetric catalysis. Isolation and comprehensive characterization of the reaction intermediates support a catalysis cycle proposed by DFT calculations.

Rhodium Catalyzed Asymmetric Hydrogenation of 2-Pyridine Ketones

Catalyzed by [Rh(COD)Binapine]BF4, the asymmetric hydrogenation of 2-pyridine ketones has been achieved with excellent enantioselectivities (enantiomeric excesses up to 99%) under mild conditions. This method is suitable for various kinds of 2-pyridine ketones and their derivatives. A number of enantiomerically pure chiral 2-pyridine-aryl/alkyl alcohols were prepared through hydrogenation, which can be used directly in organic synthesis.

Charge migration in dicationic electrophiles and its application to the synthesis of aza-polycyclic aromatic compounds

Superacid-promoted reactions of dicationic electrophiles have been studied, and the positive charge centers are found to migrate apart in a predictable manner. Using isotopic labeling the charge migration is found in one system to occur through successive deprotonation-reprotonation steps. The charge migration chemistry is the basis for new general synthetic route to aza-polycyclic aromatic compounds.