20618-42-2

Basic information

• Product Name: 2-(hydroxyMethyl)cyclopentanone
• Synonyms: 2-(hydroxyMethyl)cyclopentanone
• CAS NO: 20618-42-2
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.1424
• Mol File: 20618-42-2.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(hydroxyMethyl)cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(hydroxyMethyl)cyclopentanone(20618-42-2)
• EPA Substance Registry System: 2-(hydroxyMethyl)cyclopentanone(20618-42-2)

Safety Data

• Hazardous Substances Data: 20618-42-2(Hazardous Substances Data)

Usage

General Description

2-(Hydroxymethyl)cyclopentanone is a chemical compound with the molecular formula C6H10O2. It is a colorless, viscous liquid with a sweet, floral odor. 2-(hydroxyMethyl)cyclopentanone is used in the production of pharmaceuticals, perfumes, and flavorings due to its pleasant aroma. It is also employed as a precursor in the synthesis of various organic compounds. Additionally, 2-(hydroxymethyl)cyclopentanone is used as a solvent in some chemical processes and as a chemical intermediate in organic synthesis. It is important to handle this compound with care and follow safety guidelines, as it can be hazardous if not properly handled.

Upstream product

• 23153-74-4 (1,4-dioxa-spiro[4.4]non-6-yl)-methanol 
• 14579-07-8 1-(trimethylsilyl)cyclopentene 
• 138380-10-6 ethyl (trimethylsilyloxy)methyl sulfide 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 50-00-0 formaldehyd 
• 120-92-3 cyclopentanone 
• 1883-85-8 cis-2-(hydroxymethyl)cyclopentanol 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 110295-58-4 1,4-dioxa-spiro[4.4]nonane-6-carboxylic acid methyl ester 
• 23153-73-3 ethyl 1,4-dioxaspiro[4,4]nonane-6-carboxylate 
• 69618-32-2 2-hydroxycyclopentane-1-methanol 

Downstream Products

• 23153-74-4 (1,4-dioxa-spiro[4.4]non-6-yl)-methanol 
• 183182-18-5 (S)-2-({2-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-1-fluoro-eth-(Z)-ylidene]-cyclopentanecarbonyl}-amino)-3-phenyl-propionic acid tert-butyl ester 
• 160030-58-0 (S)-2-({(R)-2-[2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-1-fluoro-eth-(E)-ylidene]-cyclopentanecarbonyl}-amino)-3-phenyl-propionic acid tert-butyl ester 
• 160081-15-2 (S)-2-({(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-1-fluoro-eth-(E)-ylidene]-cyclopentanecarbonyl}-amino)-3-phenyl-propionic acid tert-butyl ester 
• 68755-19-1 trans-2-hydroxycyclopentanemethanol cyclic phosphoric acid phenyl ester 
• 175398-30-8 (S)-2-(((tert-butyldiphenylsilyl)oxy)methyl)cyclopentanone 

Relevant articles and documents

Chemoselective, iron(ii)-catalyzed oxidation of a variety of secondary alcohols over primary alcohols utilizing H2O2 as the oxidant

A mild, iron-based catalyst system is presented that selectively oxidizes secondary alcohols to the corresponding hydroxy ketones in the presence of primary alcohols within 15 minutes at room temperature, utilizing H 2O2 as the oxidant.

Z-Selective Horner-Wadsworth-Emmons reaction of 2-TOM-cyclopentanone for the synthesis of rac-N-Cbz-Gly-Ψ[(Z)-CFC]-Pro-OH dipeptide isostere

The Horner-Wadsworth-Emmons reactions of 2-fluoro-2-diethylphosphonoacetic acid with 2-{[(triisopropylsilyl)oxy]methyl}cyclopentanone (2-TOM-cyclopentanone) using methylmagnesium chloride furnished the corresponding tetra-substituted fluoroolefin in a Z-selective manner (E/Z = 9:91). A facile synthesis of rac-N-Cbz-Gly-Ψ[(Z)-CFC]-Pro-OH as a dipeptide isostere was achieved based on the Z-selective Horner-Wadsworth-Emmons reaction.

Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide

A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).