206532-55-0Relevant articles and documents
A new divergent asymmetric synthesis of (+)- and (-)-ethosuximides and their anticonvulsant activities
Katoh, Takahiro,Nishide, Kiyoharu,Node, Manabu,Ogura, Hiroo
, p. 833 - 841 (2007/10/03)
Both enantiomers of ethosuximide were synthesized divergently from nitroolefin lactone [(-)-2a] or [(-)-2b], which was obtained by asymmetric nitroolefination of α-methyl-γ-butyrolactone with chiral nitro enamines derived from L-proline. Although anticonv