2069-49-0Relevant articles and documents
A novel series of thiazolyl-pyrazoline derivatives: Synthesis and evaluation of antifungal activity, cytotoxicity and genotoxicity
Altintop, Mehlika Dilek,?demir, Ahmet,Turan-Zitouni, Gülhan,Ilgin, Sinem,Atli, ?zlem,Demirel, Rasime,Kaplancikli, Zafer Asim
, p. 342 - 352 (2015)
In the current work, new thiazolylepyrazoline derivatives (1e22) were synthesized and evaluated for their antifungal effects against pathogenic yeasts and molds using a broth microdilution assay. Ames assay was carried out to determine the genotoxicity of
Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors
Mathew, Bijo,Haridas, Abitha,U?ar, Gülberk,Baysal, Ipek,Adeniyi, Adebayo A.,Soliman, Mahmoud E.S.,Joy, Monu,Mathew, Githa Elizabeth,Lakshmanan, Baskar,Jayaprakash, Venkatesan
, p. 680 - 695 (2016/07/06)
Chalcone has been reported to be a valid scaffold for the design of monoamine oxidase (MAO) inhibitors. This scenario has amplified the momentum for the discovery of heteroaryl based chalcone MAO inhibitors. In the present study, we have synthesized a ser
Heteroaryl chalcones: Design, synthesis, X-ray crystal structures and biological evaluation
Chidan Kumar,Loh, Wan-Sin,Ooi, Chin Wei,Quah, Ching Kheng,Fun, Hoong-Kun
, p. 12707 - 12724 (2013/11/06)
Chalcone derivatives have attracted increasing attention due to their numerous pharmacological activities. Changes in their structures have displayed high degree of diversity that has proven to result in a broad spectrum of biological activities. The pres