207597-97-5

Basic information

• Product Name: 12aα-hydroxydeguelin
• CAS NO: 207597-97-5
• Molecular Weight: 410.423
• Mol File: 207597-97-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 12aα-hydroxydeguelin(CAS DataBase Reference)
• NIST Chemistry Reference: 12aα-hydroxydeguelin(207597-97-5)
• EPA Substance Registry System: 12aα-hydroxydeguelin(207597-97-5)

Safety Data

• Hazardous Substances Data: 207597-97-5(Hazardous Substances Data)

Upstream product

• 372-20-3 3-fluorophenol 
• 185913-28-4 2-(3-fluorophenoxy)tetrahydro-2H-pyran 
• 522-17-8 (-)-deguelin 

Relevant articles and documents

General Synthetic Approach to Rotenoids via Stereospecific, Group-Selective 1,2-Rearrangement and Dual S N Ar Cyclizations of Aryl Fluorides

A general synthetic approach to rotenoids is described, featuring 1) stereospecific, group-selective 1,2-rearrangements of epoxy alcohols, and 2) S N Ar oxy-cyclizations of aryl fluorides. The common intermediate epoxyketone, en route to (-)-rotenone and (-)-deguelin, was prepared from d -araboascorbic acid in five steps. Also described is the conversion of (-)-deguelin into oxidized congeners, (-)-tephrosin and (+)-12a- epi -tephrosin.