207619-48-5

Basic information

• Product Name: (1-METHYL-1H-INDOL-3-YL)(PIPERIDINO)METHANONE
• Synonyms: (1-METHYL-1H-INDOL-3-YL)(PIPERIDINO)METHANONE;1-methyl-3-(piperidine-1-carbonyl)-1H-indole
• CAS NO: 207619-48-5
• Molecular Formula: C15H18N2O
• Molecular Weight: 242.32
• Mol File: 207619-48-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1-METHYL-1H-INDOL-3-YL)(PIPERIDINO)METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (1-METHYL-1H-INDOL-3-YL)(PIPERIDINO)METHANONE(207619-48-5)
• EPA Substance Registry System: (1-METHYL-1H-INDOL-3-YL)(PIPERIDINO)METHANONE(207619-48-5)

Safety Data

• Hazardous Substances Data: 207619-48-5(Hazardous Substances Data)

Upstream product

• 318-54-7 2,2,2-trifluoro-1-(1-methyl-1H-indol-3-yl)ethan-1-one 
• 4442-11-9 lithium piperidide 
• 27393-79-9 (1H-indol-3-yl)(piperidin-1-yl)methanone 
• 74-88-4 methyl iodide 
• 352464-36-9 (2-bromo-1-methyl-1H-indol-3-yl)-piperidin-1-yl-methanone 
• 120-72-9 indole 
• 14618-45-2 2,2,2-trifluoro-1-(1H-indol-3-yl)ethanone 
• 110-89-4 piperidine 
• 603-76-9 1-methylindole 
• 67-66-3 chloroform 

Relevant articles and documents

A novel radical cyclization of 2-bromoindoles. Synthesis of hexahydropyrrolo[3,4-b]indoles

Hexahydropyrrolo[3,4-b]indoles 6, 10, and 13 are obtained from 2-bromo-3-carboxamides 5, 9, and 12, respectively, by a 1,5-radical translocation process followed by 5-endo-trig cyclization to the indole C-2 position.

Synthesis of indole-3-carboxamides via a haloform cleavage reaction of 3-trifluoroacetylindole with lithium dialkylamides

Reaction of 3-trifluoroacetylindole (4) with lithium dialkylamides affords the corresponding indole-3-carboxamides (5) in good to excellent yields.