207731-73-5Relevant articles and documents
Antimalarial cyclic peroxy ketals
Posner, Gary H.,O'Dowd, Hardwin,Ploypradith, Poonsakdi,Gumming, Jared N.,Xie, Suji,Shapiro, Theresa A.
, p. 2164 - 2167 (2007/10/03)
Over 20 new, cyclic, peroxy ketals have been prepared via a two-step protocol starting with readily available aryl methyl ketones. Structure- activity correlations using in vitro anti-malarial data as a guide for optimization of potency have led to the de