208665-44-5Relevant articles and documents
Solid-phase synthesis of 1,3-azole-based peptides and peptidomimetics
Biron, Eric,Chatterjee, Jayanta,Kessler, Horst
, p. 2417 - 2420 (2007/10/03)
We report highly efficient two-step procedures for the synthesis of 1,3-oxazole-, thiazole-, and imidazole-containing peptides on solid phase from dipeptides composed of C-terminal threonine, serine, cysteine, or diaminopropionic acid by using different cyclodehydration procedures followed or preceded by oxidation. The methods are compatible with Fmoc solid-phase peptide synthesis conditions and with N-Fmoc, N-Boc, N-Cbz, and N-Alloc protecting groups.