20877-88-7

Basic information

• Product Name: Benzenemethanamine, 2-(methylamino)-
• CAS NO: 20877-88-7
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Mol File: 20877-88-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, 2-(methylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, 2-(methylamino)-(20877-88-7)
• EPA Substance Registry System: Benzenemethanamine, 2-(methylamino)-(20877-88-7)

Safety Data

• Hazardous Substances Data: 20877-88-7(Hazardous Substances Data)

Upstream product

• 7505-81-9 2-methylaminobenzamide 
• 53378-34-0 1,2-dihydro-quinazoline 
• 10328-92-4 N-Methylisatoic anhydride 
• 1885-29-6 anthranilic acid nitrile 
• 253-82-7 quinazoline 
• 119-68-6 N-Methylanthranilic acid 

Downstream Products

• 404387-08-2 (2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-[4-(2-methylamino-benzylcarbamoyloxymethyl)-2-nitro-phenoxy]-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 1621054-04-3 C₉H₁₀N₂S 
• 1621054-05-4 C₁₅H₁₅N₃ 
• 229326-23-2 ethyl N-(2-(benzyloxycarbonylamino)benzyl)-N-methylcarbamate 
• 404387-09-3 (2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-(4-{2-[(4,5-dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 404387-10-6 (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 404387-11-7 (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid 
• 145429-23-8 [2-(Isopropylamino-methyl)-phenyl]-methyl-amine 

Relevant articles and documents

Three-component (Domino) reaction affording substituted pyrroloquinazolines: Cyclization regioselectivity and stereoselectivity

The cyclization involving 2-(aminomethyl)aniline, methyl 3,3,3-trifluoropyruvate, and various oxo compound afforded linearly annulated pyrroloquinazolines, for example, (2R,3aS)-2-hydroxy-3a-phenyl-2- trifluoromethyl-3,3a,4,9-tetrahydropyrrolo[2,1-b]quina

Synthesis and β-glucuronidase mediated cleavage of an alcohol prodrug incorporating a double spacer moiety

An alcohol prodrug has been prepared by incorporation of two spacer groups between the trigger (glucuronic acid) and nitroveratryl alcohol, used as a model. Release of the later has been observed after hydrolysis of the glycoside by β-glucuronidase. Such prodrugs may find application in ADEPT or PMT potocols in cancer chemotherapy.

Properties of Bis(trifluoroacetoxy)borane as a Reducing Agent of Organic Compounds

Reactions of bis(trifluoroacetoxy)borane-THF (1) with compounds containing representative organic functional groups were studied to determine the usefulness of 1 as a selective reducing agent.Reducible functionalities were indoles, ketones, aldehydes, imines, and compounds that readily generate carbocations in trifluoroacetic acid.Many functionalities were inert to 1.Epoxides and ortho esters suffered decomposition under the reaction conditions.Olefins and acetylenes were not hydroborated, and carboxylic acids were not reduced by 1.