404387-11-7

Basic information

• Product Name: (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid
• Synonyms: (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid
• CAS NO: 404387-11-7
• Molecular Weight: 746.639
• Mol File: 404387-11-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid(404387-11-7)
• EPA Substance Registry System: (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid(404387-11-7)

Safety Data

• Hazardous Substances Data: 404387-11-7(Hazardous Substances Data)

Upstream product

• 1885-29-6 anthranilic acid nitrile 
• 404387-08-2 (2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-[4-(2-methylamino-benzylcarbamoyloxymethyl)-2-nitro-phenoxy]-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 17583-40-3 2-methylaminobenzonitrile 
• 404387-10-6 (2S,3S,4S,5R,6S)-6-(4-{2-[(4,5-Dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 404387-09-3 (2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-(4-{2-[(4,5-dimethoxy-2-nitro-benzyloxycarbonyl)-methyl-amino]-benzylcarbamoyloxymethyl}-2-nitro-phenoxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 20877-88-7 2-(aminomethyl)-N-methylaniline 

Downstream Products

• 41833-13-0 4-hydroxymethyl-2-nitrophenol 

Relevant articles and documents

Synthesis and β-glucuronidase mediated cleavage of an alcohol prodrug incorporating a double spacer moiety

An alcohol prodrug has been prepared by incorporation of two spacer groups between the trigger (glucuronic acid) and nitroveratryl alcohol, used as a model. Release of the later has been observed after hydrolysis of the glycoside by β-glucuronidase. Such prodrugs may find application in ADEPT or PMT potocols in cancer chemotherapy.