208941-47-3

Basic information

• Product Name: 3'-(Hydroxymethyl)-biphenyl-4-carboxaldehyde
• Synonyms: 3'-(Hydroxymethyl)-biphenyl-4-carboxaldehyde
• CAS NO: 208941-47-3
• Molecular Formula: C14H12O2
• Molecular Weight: 212.24388
• Mol File: 208941-47-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3'-(Hydroxymethyl)-biphenyl-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-(Hydroxymethyl)-biphenyl-4-carboxaldehyde(208941-47-3)
• EPA Substance Registry System: 3'-(Hydroxymethyl)-biphenyl-4-carboxaldehyde(208941-47-3)

Safety Data

• Hazardous Substances Data: 208941-47-3(Hazardous Substances Data)

Upstream product

• 87199-17-5 4-formylphenylboronic acid, 
• 208941-39-3 4-(4-Carboxy-butoxy)-benzoic acid 3-iodo-benzyl ester 
• 35005-21-1 4-(4-Carboxy-butoxy)-benzoic acid 
• 1122-91-4 4-bromo-benzaldehyde 
• 87199-15-3 [3-(hydroxymethyl)phenyl]boronic acid 

Relevant articles and documents

BENZIMIDAZOLE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY

A compound of formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the compound. The compound is useful in therapy, for the treatment of disorders mediated by HDAC6, such as autoimmune disorders, neurodege

Development of unimolecular tetrakis(piperidin-4-ol) as a ligand for Suzuki-Miyaura cross-coupling reactions: Synthesis of incrustoporin and preclamol

Abstract A domino aza-Cope/aza-Prins cascade enabled the synthesis of a new class of 4-hydroxypiperidine-appended mono, bis, tris, and tetrakis unimolecular compounds that served as efficient ligands to catalyze Suzuki-Miyaura cross-coupling reactions under aerobic conditions. Various biaryls, terphenyls, and heterocyclic biphenyls were obtained in good to excellent yields. The ligands were also capable of catalyzing the Heck-Mizoroki reaction. As an application, the Suzuki-Miyaura coupling reaction was used in the synthesis of incrustoporin, its analogs, and the drug molecule preclamol. A domino aza-Cope/aza-Prins cascade enabled the synthesis of a new class of 4-hydroxypiperidine-appended mono-, bis-, tris-, and tetrakis-unimolecular compounds that served as efficient ligands to catalyze Suzuki-Miyaura cross-coupling reactions under aerobic conditions. Various biaryls, terphenyls, and heterocyclic biphenyls were obtained in good to excellent yields.