35005-21-1

Basic information

• Product Name: 4-(4-Carboxy-butoxy)-benzoic acid
• Synonyms: 4-(4-Carboxy-butoxy)-benzoic acid
• CAS NO: 35005-21-1
• Molecular Weight: 238.24
• Mol File: 35005-21-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-Carboxy-butoxy)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Carboxy-butoxy)-benzoic acid(35005-21-1)
• EPA Substance Registry System: 4-(4-Carboxy-butoxy)-benzoic acid(35005-21-1)

Safety Data

• Hazardous Substances Data: 35005-21-1(Hazardous Substances Data)

Upstream product

• 88987-42-2 tert-butyl 5-bromovalerate 
• 2067-33-6 5-bromopentanoic acid 
• 208941-36-0 4-(4-tert-Butoxycarbonyl-butoxy)-benzoic acid benzyl ester 

Downstream Products

• 208941-39-3 4-(4-Carboxy-butoxy)-benzoic acid 3-iodo-benzyl ester 
• 123926-48-7 (3-(benzylthio)phenyl)methanol 
• 208941-54-2 (2'-methoxybiphenyl-3-yl)methanol 
• 208941-51-9 (3',5'-Dichloro-biphenyl-3-yl)-methanol 
• 208941-47-3 3'-(hydroxymethyl)[1,1'-biphenyl]-4-carbaldehyde 
• 208941-45-1 3-amino-3'-hydroxymethylbiphenyl 
• 76350-85-1 (2'-methyl-[1,1'-biphenyl])-3-methanol 
• 85553-54-4 (3-(pyridin-3-yl)phenyl)methanol 
• 89929-82-8 (3-thiophen-3-yl-phenyl)methanol 
• 89929-93-1 3-(furan-2-yl)benzyl alcohol 
• 126485-55-0 (4'-Trifluoromethyl-biphenyl-3-yl)-methanol 
• 89951-79-1 (4'-methylbiphenyl-3-yl)methanol 

Relevant articles and documents

Pd-mediated C-C and C-S bond formation on solid support: A scope and limitations study

The scope and limitations of Pd(0)-mediated coupling reactions between aromatic halides linked to a polystyrene resin and boronic acid derivatives (Suzuki coupling), aromatic and vinylic tin compounds (Stille coupling), as well as thiols are reported. For all reactions, conditions were optimized and evaluated with various reagents. In many cases, upon cleavage from the solid support, products were obtained in excellent yields. In most cases, the optimized reaction conditions are superior to those previously reported in the literature.