20939-16-6

Basic information

• Product Name: 4-AMINO-5-ETHYL-4H-1,2,4-TRIAZOLE-3-THIOL, 97
• Synonyms: 4-AMINO-5-ETHYL-4H-1,2,4-TRIAZOLE-3-THIOL, 97;3H-1,2,4-Triazole-3-thione,4-amino-5-ethyl-2,4-dihydro-(9CI);4-Amino-5-ethyl-3-mercapto-4H-1,2,4-triazole
• CAS NO: 20939-16-6
• Molecular Formula: C₄H₈N₄S
• Molecular Weight: 144.201
• Product Categories: THIOL
• Mol File: 20939-16-6.mol
• Article Data: 20

Chemical Properties

• Melting Point: 184℃
• Boiling Point: 213.7°Cat760mmHg
• Flash Point: 83°C
• Appearance: /
• Density: 1.55g/cm³
• Vapor Pressure: 0.162mmHg at 25°C
• Refractive Index: 1.741
• PKA: 9.20±0.20(Predicted)
• CAS DataBase Reference: 4-AMINO-5-ETHYL-4H-1,2,4-TRIAZOLE-3-THIOL, 97(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-5-ETHYL-4H-1,2,4-TRIAZOLE-3-THIOL, 97(20939-16-6)
• EPA Substance Registry System: 4-AMINO-5-ETHYL-4H-1,2,4-TRIAZOLE-3-THIOL, 97(20939-16-6)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• HazardClass: IRRITANT
• Hazardous Substances Data: 20939-16-6(Hazardous Substances Data)

Usage

General Description

4-AMINO-5-ETHYL-4H-1,2,4-TRIAZOLE-3-THIOL, 97 is a chemical compound with a purity of 97%. It is a triazole derivative with a substituted amino group and a thiol group. 4-AMINO-5-ETHYL-4H-1,2,4-TRIAZOLE-3-THIOL, 97 is commonly used in organic synthesis and as an intermediate in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. It is also used in research and development and in the manufacturing of dyes and pigments. Additionally, this compound has potential applications in the field of materials science and as a building block for diverse chemical reactions due to its unique structure and reactivity.

InChI:InChI=1/C4H8N4S/c1-2-3-6-7-4(9)8(3)5/h2,5H2,1H3,(H,7,9)

Upstream product

• 90992-69-1 C₄H₇N₂OS₂^(1-)*K⁽¹⁺⁾ 
• 802294-64-0 propionic acid 
• 2231-57-4 Thiocarbohydrazide 
• 79-19-6 thiosemicarbazide 
• 75-15-0 carbon disulfide 
• 5818-15-5 d'hydrazide de l'acide propionique 
• 6610-29-3 4-methylthiosemicarbazide 

Downstream Products

• 24848-30-4 3-ethyl-6-pyridin-2-yl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 24852-22-0 3-ethyl-6-phenyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole 
• 24852-23-1 6-(p-Tolyl)-3-aethyl-1.2.4-triazolo<3.4-b><1.3.4>thiadiazol 
• 43029-42-1 3-ethyl-6-styryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 68469-04-5 7H-3-Ethyl-6-(p-diphenyl)-s-triazolo<3,4-b><1,3,4>thiadiazin 
• 24848-29-1 3-ethyl-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 68468-99-5 6-(4-chloro-phenyl)-3-ethyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 3173-12-4 3-Aethyl-s-triazolo<3,4-b><1,3,4>thiadiazol-6-thiol 
• 3176-52-1 6-amino-3-ethyl-s-triazolo-[3,4-b][1,3,4]thiadiazole 
• 139267-96-2 4-<5-(4-p-Chlorophenyl)-2-furfurylidene>amino-3-mercapto-5-ethyl-1,2,4-triazole 
• 139268-14-7 6-<5-(4-Chlorophenyl)-2-furyl>-3-ethyl-1,2,4-triazolo<3,4-b>-1,3,4-thiadiazole 
• 139267-84-8 4-<5-(4-p-Nitrophenyl)-2-furfurylidene>amino-3-mercapto-5-ethyl-1,2,4-triazole 
• 139268-02-3 6-<5-(4-Nitrophenyl)-2-furyl>-3-ethyl-1,2,4-triazolo<3,4-b>-1,3,4-thiadiazole 
• 60783-86-0 N¹-phenyl-N³-(3-mercapto-5-ethyl)-1,2,4-triazol-4-yl thiourea 

Relevant articles and documents

Laccase Enzyme Catalysed Efficient Synthesis of 3-Substituted-1,2,4-Triazolo(4,3-b)(4,1,2)Benzothiadiazine-8-Ones

Full details of an efficient one step synthesis of substituted(4,3-b)(4,1,2)benzothiadiazine-8-ones (4a-4h) by Laccase enzyme (E.C.1.10.3.2) mediated reaction of various 5-substituted-4-amino-3-mercapto-1,2,4-triazoles (1a-1h) and hydroquinone (2) is desc

Synthesis and characterization of novel Cu (II) complexes with 3-substituted-4-amino-5-mercapto-1,2,4-triazole Schiff bases: A new route to CuO nanoparticles

Cu (II) complexes, were synthesized with newly derived biologically active 1,2,4-triazole Schiff bases. The Schiff bases were synthesized by condensation of 3-substituted-4-amino-5-mercapto-1,2,4-triazole with dibenzoylmethane. The synthesized compounds were characterized using elemental analysis, magnetic moment, thermal analysis and spectral tools (FT-IR, 1HNMR, ESR, and UV-Vis spectroscopy). All the synthesized complexes are nonelectrolytes in N,N-dimethylformamide. The synthesized Schiff bases and their Cu (II) complexes have been screened for antibacterial (Escherichia coli & Staphylococcus aureus) and antifungal (Aspergillus flavus & Candida albicans) activity using a modified Bauer-Kirby method. Interestingly, the synthesized Cu (II) complexes were used as precursors for CuO nanoparticles which were characterized using XRD, HR-TEM, FT-IR and UV-Vis spectroscopy. The photocatalytic activity of the prepared CuO nanoparticles was studied by performing the degradation of methylene blue dye under UV illumination in the presence of H2O2 and the results showed that the maximum percent of the degradation of methylene blue dye (MB) was found 96.18% after 360 min.

1,2,4-triazole-3-thione Schiff bases compounds: Crystal structure, hirshfeld surface analysis, DFT studies and biological evaluation

Three novel Schiff base compounds (G1, G2 and G3) were synthesized and characterized by elemental analysis, FT-IR, NMR, and X-ray single crystal diffraction. The crystal structures exhibit both inter- and intra-molecular h

Synthesis and biological evaluation of some novel S-β-D-glucosides of 4-amino-5-alkyl-1,2,4-triazole-3-thiones derivatives

A novel series of 3-S-β-D-glucosides-4-arylideneamino-5-alkyl-1,2,4-triazoles were designed and synthesized by reaction of 4-amino-5-alkyl-4H-1,2,4triazole-3-thiol Schiff bases and 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide. The structures of the target compounds have been characterized by 1H NMR, 13C NMR, FT-IR, and Microanalyses. All the newly synthesized compounds have been screened for their in vitro antibacterial and antifungal activities against two Gram-positive bacteria [Bacillus cereus (PTCC 1015) and Staphylococcus aureus (ATCC 25923)], two Gram-negative bacteria [Pseudomonas aeruginosa (ATCC 27853) and Escherichia coli (PTCC 1399) and two fungi [Aspergillus Niger (PTCC 5012) and Candida albicans (PTCC 5027)].