209479-86-7

Basic information

• Product Name: (2R,3R)-3-O-tert-butyldiphenylsilyl-1,2-O-isopropylidene-4-pentene-1,2,3-triol
• Synonyms: (2R,3R)-3-O-tert-butyldiphenylsilyl-1,2-O-isopropylidene-4-pentene-1,2,3-triol
• CAS NO: 209479-86-7
• Molecular Weight: 396.602
• Mol File: 209479-86-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2R,3R)-3-O-tert-butyldiphenylsilyl-1,2-O-isopropylidene-4-pentene-1,2,3-triol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-3-O-tert-butyldiphenylsilyl-1,2-O-isopropylidene-4-pentene-1,2,3-triol(209479-86-7)
• EPA Substance Registry System: (2R,3R)-3-O-tert-butyldiphenylsilyl-1,2-O-isopropylidene-4-pentene-1,2,3-triol(209479-86-7)

Safety Data

• Hazardous Substances Data: 209479-86-7(Hazardous Substances Data)

Upstream product

• 18524-18-0 (R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)prop-2-en-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 212579-64-1 (4R)-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)allyl alcohol 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 102357-25-5 (1S,4'R)-1-(2,2-dimethyl-1,3-dioxolane-4-yl)-2-trimethylsilylprop-2-en-1-ol 
• 71769-39-6 (4S,5S,4'R)-5-Iodomethyl-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl] 
• 87678-03-3 Toluene-4-sulfonic acid (4S,5S,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-ylmethyl ester 
• 109836-16-0 1-iodo-1-deoxy-2,3:4,5-di-O-isopropylidene-D-xylitol 
• 30737-85-0 2,3,4,5-di-O-isopropylidene-D-xylitol 

Downstream Products

• 209479-88-9 tert-butyl((S)-1-penten-4-yn-3-yloxy)diphenylsilane 
• 209479-87-8 tert-Butyl-((S)-3,3-dibromo-1-vinyl-allyloxy)-diphenyl-silane 
• 18524-18-0 (R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)prop-2-en-1-ol 
• 334784-91-7 (2R,3R)-3-O-tert-butyldiphenylsilyl-4-pentene-1,2,3-triol 
• 239473-45-1 (3R,9S,10S)-10-tert-butyldimethylsilyloxy-3-tert-butyldiphenylsilyloxy-heptadec-1-ene-4,6-diyne-9-ol 
• 224636-43-5 (3R)-1,1-dibromo-3-tert-butyldiphenylsilyloxy-1,4-pentdiene 
• 224636-36-6 3(R)-(tert-butyldiphenylsilyloxy)-1-penten-4-yne 
• 209479-94-7 (3R,9R,10R)-10-tert-butyldimethylsilyloxy-3-tert-butyldiphenylsilyloxy-heptadec-1-ene-4,6-diyne-9-ol 
• 303158-64-7 (E)-(R)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-but-2-enoic acid ethyl ester 
• 303158-52-3 tert-Butyl-[(E)-(R)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxy-3-methyl-but-2-enyloxy]-diphenyl-silane 
• 303158-66-9 (E)-(2R,3R)-3-(tert-Butyl-diphenyl-silanyloxy)-6-methoxymethoxy-5-methyl-hex-4-ene-1,2-diol 
• 303158-65-8 (E)-(R)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-but-2-en-1-ol 
• 303158-53-4 (E)-(R)-2-(tert-Butyl-diphenyl-silanyloxy)-5-methoxymethoxy-4-methyl-pent-3-enal 
• 303158-51-2 (S)-(tert-Butyl-diphenyl-silanyloxy)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-acetaldehyde 

Relevant articles and documents

First total synthesis of panaxytriol, a potent antitumor agent isolated from Panax ginseng

Panaxytriol 1, a potent antitumor agent isolated from Panax ginseng, was first synthesized, and its stereostructure was confirmed to be (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10-triol.

Synthetic studies toward phorboxazole A. stereoselective synthesis of the C(28)-C(46) side chain fragment.

A stereoselective synthesis of the C(28)-C(46) fragment (3) of phorboxazole A is described. Key advances include an enantioselective allylation to establish the stereochemistry of the tetrahydropyran unit and a useful SmI(2)-mediated modification of the B