210232-93-2

Basic information

• Product Name: ethyl 2-amino-2',5-dioxo-1',3',5,6,7,8-hexahydrospiro[4H-chromene-4,3'-(2'H)-indole]-3-carboxylate
• Synonyms: ethyl 2-amino-2',5-dioxo-1',3',5,6,7,8-hexahydrospiro[4H-chromene-4,3'-(2'H)-indole]-3-carboxylate
• CAS NO: 210232-93-2
• Molecular Formula: C19H18N2O5
• Molecular Weight: 354.35662
• Mol File: 210232-93-2.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 2-amino-2',5-dioxo-1',3',5,6,7,8-hexahydrospiro[4H-chromene-4,3'-(2'H)-indole]-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-amino-2',5-dioxo-1',3',5,6,7,8-hexahydrospiro[4H-chromene-4,3'-(2'H)-indole]-3-carboxylate(210232-93-2)
• EPA Substance Registry System: ethyl 2-amino-2',5-dioxo-1',3',5,6,7,8-hexahydrospiro[4H-chromene-4,3'-(2'H)-indole]-3-carboxylate(210232-93-2)

Safety Data

• Hazardous Substances Data: 210232-93-2(Hazardous Substances Data)

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 14003-19-1 ethyl cyano-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)acetate 
• 14003-18-0 ethyl 2-(2-oxoindolin-3-ylidene)cyanoacetate 
• 6532-16-7 1-(4-morpholinylmethyl)-1H-indole-2,3-dione 
• 105-56-6 ethyl 2-cyanoacetate 
• 91-56-5 indole-2,3-dione 

Relevant articles and documents

One-pot synthesis of spirooxindole derivatives catalyzed by lipase in the presence of water

A facile one-pot synthesis route to spirooxindole derivatives was developed by combining the three types of catalytic activities of lipase from porcine pancreas (PPL) in the presence of water, i.e., the Knoevengel condensation, Michael addition and cyclization. PPL showed excellent catalytic activity and have a good adaptability to different substrates in the reaction. All the reactions go smoothly and provide spirooxindole derivatives with high yield under the mild conditions. This lipase-catalyzed multistep conversion method has provided a new strategy to synthesize spirooxindole derivatives and expanded the application of biocatalysts.

Magnetic calcined oyster shell functionalized with taurine immobilized on β-cyclodextrin (Fe3O4/COS@β-CD-SO3H NPs) as green and magnetically reusable nanocatalyst for efficient and rapid synthesis of spirooxindoles

Abstract: Magnetic calcined oyster shell functionalized with taurine immobilized on β-cyclodextrin (Fe3O4/COS@β-CD-SO3H NPs) was prepared as a new stable, long-lived, highly efficient, and exceptional reusable magnetic nan

Caspian Isinglass, a versatile and sustainable biocatalyst for domino synthesis of spirooxindoles and spiroacenaphthylenes in water

Abstract: Isinglass, derived from swim bladders of Caspian Sea fish and consisting predominantly of protein collagen, was found to be an effective, easily accessible heterogeneous biocatalyst for the synthesis of biologically important functionalized spir

Synthesis of spirochromene derivatives catalyzed by Mn(bpyo)2/MCM-41 in water

A three-component one-pot synthesis of spirochromene derivatives by condensing cyclic 1,3-diketones, isatin or acenaphthenequinone, and malononitrile using a catalytic amount of Mn(bpyo)2/MCM-41 in refluxing water is reported.