211245-56-6

Basic information

• Product Name: 2-METHYLSULFANYL-4-PHENYLAMINO-PYRIMIDINE-5-CARBALDEHYDE
• Synonyms: 2-METHYLSULFANYL-4-PHENYLAMINO-PYRIMIDINE-5-CARBALDEHYDE;2-Methylsulfanyl-4-phenylamino-pyriomidine-5-carbaldehyde;2-(Methylthio)-4-(phenylamino)pyrimidine-5-carbaldehyde;2-Methylsulfanyl-4-phenylaMinopyriMidine-5-carboxaldehyde
• CAS NO: 211245-56-6
• Molecular Formula: C₁₂H₁₁N₃OS
• Molecular Weight: 245.3
• Product Categories: Building Blocks;Pyrimidine
• Mol File: 211245-56-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 437.031°C at 760 mmHg
• Flash Point: 218.109°C
• Appearance: /
• Density: 1.311g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 2-METHYLSULFANYL-4-PHENYLAMINO-PYRIMIDINE-5-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLSULFANYL-4-PHENYLAMINO-PYRIMIDINE-5-CARBALDEHYDE(211245-56-6)
• EPA Substance Registry System: 2-METHYLSULFANYL-4-PHENYLAMINO-PYRIMIDINE-5-CARBALDEHYDE(211245-56-6)

Safety Data

• Hazardous Substances Data: 211245-56-6(Hazardous Substances Data)

Usage

General Description

2-METHYLSULFANYL-4-PHENYLAMINO-PYRIMIDINE-5-CARBALDEHYDE is a chemical compound with a complex molecular structure. It contains a pyrimidine ring with a methylsulfanyl group at the 2-position and a phenylamino group at the 4-position. Additionally, it has a carbinaldehyde group at the 5-position. 2-METHYLSULFANYL-4-PHENYLAMINO-PYRIMIDINE-5-CARBALDEHYDE may have potential applications in pharmaceutical research and drug development, as its unique structure could make it suitable for targeting specific biological pathways or interactions. Further exploration of its properties and potential uses could provide valuable insights for the development of new therapeutic agents.

InChI:InChI=1/C12H11N3OS/c1-17-12-13-7-9(8-16)11(15-12)14-10-5-3-2-4-6-10/h2-8H,1H3,(H,13,14,15)

Upstream product

• 211245-55-5 (2-Methanesulfanyl-4-phenylamino-pyrimidin-5-yl)-methanol 
• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 62-53-3 aniline 
• 106475-47-2 2-methanesulfanyl-4-phenylamino-pyrimidine-5-carboxylic acid ethyl ester 
• 185040-34-0 (4-ethylamino-2-methanesulfanyl-pyrimidin-5-yl)-methanol 

Downstream Products

• 211245-58-8 2-Methanesulfanyl-8-phenyl-8H-pyrido[2,3-d]pyrimidin-7-one 
• 211245-59-9 2-methanesulfinyl-8-phenyl-8H-pyrido[2,3-d]pyrimidin-7-one 
• 335653-81-1 5-(2-chlorophenyl)aminomethyl-4-phenylamino-2-methylthiopyrimidine 

Relevant articles and documents

A facile, KF/Al2O3 mediated method for the preparation of functionalized pyrido[2,3-d]pyrimidin-7(8H)-ones

A series of functionalized pyrido[2,3-d]pyrimidin-7(8H)-ones were prepared by a KF/Al2O3 mediated condensation of 4-(alkylamino)-2-(methylthio)pyrimidine-5-carbaldehydes and phenyl acetic acid ester derivatives.

Pyrido[2,3-D]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation

This invention provides pyridopyrimidines and 4-aminopyrimidines that are useful for treating cell proliferative disorders, such as cancer and restenosis. We have now discovered a group of 7,8-dihydro-2-(amino and thio)pyrido[2,3-d]pyrimidines and 2,4-dia

Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases

The identification of 8-ethyl-2-phenylamino-8H-pyrido [2,3-d]pyrimidin-7-one (1) as an inhibitor of Cdk4 led to the initiation of a program to evaluate related pyrido [2,3-d]pyrimidin-7-ones for inhibition of cyclin-dependent kinases (Cdks). Analysis of m