211374-81-1 Usage
Description
4-amino-2-chlorobenzamide is an organic compound with the molecular formula C7H7ClN2O. It is a derivative of benzamide, featuring an additional amino group at the 4-position and a chlorine atom at the 2-position. 4-amino-2-chlorobenzamide is known for its potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
4-amino-2-chlorobenzamide is used as a reagent for the synthetic preparation of phenylaminopyrimidine derivatives. These derivatives are known to act as protein kinase inhibitors, which play a crucial role in the regulation of various cellular processes, including signal transduction, cell growth, and apoptosis. In the pharmaceutical industry, these inhibitors are being developed as potential therapeutic agents for the treatment of various diseases, particularly cancer.
In the context of protein kinase inhibition, 4-amino-2-chlorobenzamide serves as a key intermediate in the synthesis of phenylaminopyrimidine derivatives. These derivatives have shown promise in targeting specific protein kinases, which are often dysregulated in cancer cells, leading to uncontrolled cell proliferation and tumor growth. By inhibiting these protein kinases, the phenylaminopyrimidine derivatives can potentially halt the progression of cancer and offer a new avenue for cancer treatment.
Furthermore, the development of novel drug delivery systems and the exploration of synergistic effects with conventional chemotherapeutic drugs can enhance the efficacy and bioavailability of phenylaminopyrimidine derivatives, making them more effective in combating cancer. This highlights the importance of 4-amino-2-chlorobenzamide as a reagent in the pharmaceutical industry, contributing to the development of innovative cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 211374-81-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,1,3,7 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 211374-81:
(8*2)+(7*1)+(6*1)+(5*3)+(4*7)+(3*4)+(2*8)+(1*1)=101
101 % 10 = 1
So 211374-81-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H7ClN2O/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,9H2,(H2,10,11)
211374-81-1Relevant articles and documents
HETEROCYCLIC COMPOUND
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Paragraph 1083, (2016/03/18)
The present invention provides a heterocyclic compound having an RORγt inhibitory action. The present invention relates to a compound represented by the formula (I): wherein Ar is a the partial structure (1) to the partial structure (5), Q is a bivalent group selected from the group consisting of (Ia)-(If), and B is a ring optinally having substituent(s), or a salt thereof.
Ecofriendly solvent free microwave enhanced thermal Fries rearrangement of anilides and phenyl ureas
Easwaramurthy,Ravikumar,Lakshmanan,Raju
, p. 635 - 637 (2007/10/03)
A rapid, cleaner, cost effective and ecofriendly synthesis of exclusive para aminoaryl ketones and para aminoaryl amides in solvent free conditions using solid supports under microwave irradiation is achieved.
