212248-00-5

Basic information

• Product Name: (5-METHYL-7-OXO-4,7-DIHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-ACETIC ACID
• Synonyms: (5-METHYL-7-OXO-4,7-DIHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-ACETIC ACID;(5-Methyl-7-oxo-3,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-acetic acid
• CAS NO: 212248-00-5
• Molecular Formula: C8H8N4O3
• Molecular Weight: 208.17
• Mol File: 212248-00-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (5-METHYL-7-OXO-4,7-DIHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (5-METHYL-7-OXO-4,7-DIHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-ACETIC ACID(212248-00-5)
• EPA Substance Registry System: (5-METHYL-7-OXO-4,7-DIHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-ACETIC ACID(212248-00-5)

Safety Data

• Hazardous Substances Data: 212248-00-5(Hazardous Substances Data)

Usage

Description

(5-METHYL-7-OXO-4,7-DIHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL)-ACETIC ACID, also known as MTA, is a synthetic triazolopyrimidine derivative with potential antineoplastic and immunomodulatory properties. It has been studied for its potential use in treating various types of cancer and modulating the immune system to inhibit tumor growth.
Used in Pharmaceutical Industry:
MTA is used as an antineoplastic agent for its potential to treat various types of cancer, including prostate, breast, and bladder cancer. It works by inhibiting histone deacetylase and affecting the expression of genes involved in cancer progression.
Used in Immunotherapy:
MTA is used as an immunomodulatory agent for its potential to modulate the immune system and enhance the body's natural defense mechanisms against cancer cells.

Upstream product

• 141-97-9 ethyl acetoacetate 
• 143832-52-4 2-(5-amino-1H-1,2,4-triazol-3-yl)acetic acid 

Relevant articles and documents

Applications of alkaloid essramycin and derivative thereof in resisting of plant viruses

The invention relates to applications of alkaloid essramycin and a derivative thereof in resisting of plant viruses, wherein the chemical structural formula of the alkaloid essramycin is represented in the specification, specifically the alkaloid essramyc

6-Nitro- and 6-Bromo Derivatives of 4,7-Dihydro-1,2,4-triazolo[1,5-a]pyrimidin-7-one

Cyclocondensation of 3-substituted 5-amino-1,2,4-triazoles with ethyl acetoacetate gave a series of 2-substituted 5-methyl-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidin-7-ones, including those containing functional groups in the 2-substituent. Nitration of these compounds with a mixture of sulfuric and nitric acids and bromination with bromine in alkaline medium resulted in the corresponding 6-nitro- and 6-bromo derivatives; in some cases the nitration occurred both at the pyrimidine ring and at the side chain in the triazole moiety. The bromination involved only the heteroring. Functional groups in the 2-substituent underwent transformations typical of these groups. 6-Nitro- and 6-bromo-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidin-7-ones readily form salts with nitrogen-containing organic bases.