213008-26-5

Basic information

• Product Name: (3S)-1-benzyl-3-[(5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy]tetrahydro-1H-pyrrole
• Synonyms: (3S)-1-benzyl-3-[(5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy]tetrahydro-1H-pyrrole
• CAS NO: 213008-26-5
• Molecular Weight: 323.435
• Mol File: 213008-26-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3S)-1-benzyl-3-[(5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy]tetrahydro-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-1-benzyl-3-[(5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy]tetrahydro-1H-pyrrole(213008-26-5)
• EPA Substance Registry System: (3S)-1-benzyl-3-[(5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy]tetrahydro-1H-pyrrole(213008-26-5)

Safety Data

• Hazardous Substances Data: 213008-26-5(Hazardous Substances Data)

Upstream product

• 101385-90-4 (R)-N-benzyl-3-hydroxypyrrolidine 
• 10538-48-4 2,3-dimethoxyhydrocinnamic acid 
• 7345-82-6 trans-2,3-dimethoxycinnamic acid 
• 51932-57-1 4,5-Dimethoxy indane 
• 6342-80-9 4,5-dimethoxyindanone 
• 114715-35-4 (R)-3-methanesulfonyloxy-1-(phenylmethyl)-pyrrolidine 
• 213008-03-8 5-methoxy-4-indanol 

Relevant articles and documents

Efficient synthesis of the 5-HT2C receptor agonist, Org 37684

An efficient synthesis of the 5-HT2C receptor agonist Org 37684 is presented. The synthesis utilises the regioselective demethylation of an arylether as the key step.

Derivatives of azetidine and pyrrolidine

The invention relates to a compound having the formula I wherein A is an optionally unsaturated 5- or 6-membered ring, which may comprise a heteroatom selected from N, O and S and which may be substituted with oxo or (1-6C)alkyl; R1, R2and R3are independently H, (1-6C)alkyl, (1-6C)alkoxy, (1-6C)alkoxy-(1-6C)alkyl, carbo(1-6C)alkoxy or halogen; X is O or S; and n is 1 or 2; or a pharmaceutically acceptable salt thereof, with the exception of 3-(naphth-1-yl-oxy)-pyrrolidin and 3-(5,6,7,8-tetrahydro-naphth-1-yl-oxy)-pyrrolidin., The compounds of the invention have antidepressant activity and can be used in treating or preventing serotonin-related diseases.