213672-84-5Relevant articles and documents
Stereoselective process for a CCR3 antagonist
Yue, Tai-Yuen,McLeod, Douglas D.,Albertson, Kevin B.,Beck, Steven R.,Deerberg, Joerg,Fortunak, Joseph M.,Nugent, William A.,Radesca, Lilian A.,Tang, Liya,Xiang, Cathie Dong
, p. 262 - 271 (2012/12/22)
A convergent, multikilogram, stereoselective synthesis of 1 is described. A key fragment, (S)-3-(4-fluorobenzyl)piperidine (2) was synthesized from valerolactam in three steps using our recently discovered Ir-BDPP-catalyzed asymmetric hydrogenation. Anoth
N-UREIDOALKYL-AMINO COMPOUNDS AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
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Page/Page column 126-127, (2008/06/13)
The present application describes modulators of chemokine receptors of formula (I), or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.
Enzymatic resolution of alicyclic 1,3-amino alcohols in organic media
Peter, Maria,Van Der Eycken, Johan,Bernath, Gabor,Fueloep, Ferenc
, p. 2339 - 2347 (2007/10/03)
Racemic cis- and trans-2-aminocyclohexane-1-methanol and cis- and trans- 2-amino-4-cyclohexene-1-methanol were resolved via lipase-catalysed O- acylation of their Z derivatives, using vinyl butyrate in different ether solvents. In accordance with the empi