214210-37-4

Basic information

• Product Name: (3S,4R,5S)-4-(dimethylphenylsilyl)-4,5-dihydro-5-methyl-3-(5-methylhexyl)-2(3H)-furanone
• CAS NO: 214210-37-4
• Molecular Weight: 332.558
• Mol File: 214210-37-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,4R,5S)-4-(dimethylphenylsilyl)-4,5-dihydro-5-methyl-3-(5-methylhexyl)-2(3H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R,5S)-4-(dimethylphenylsilyl)-4,5-dihydro-5-methyl-3-(5-methylhexyl)-2(3H)-furanone(214210-37-4)
• EPA Substance Registry System: (3S,4R,5S)-4-(dimethylphenylsilyl)-4,5-dihydro-5-methyl-3-(5-methylhexyl)-2(3H)-furanone(214210-37-4)

Safety Data

• Hazardous Substances Data: 214210-37-4(Hazardous Substances Data)

Upstream product

• 105881-47-8 (4S,5S)-4,5-dihydro-4-hydroxy-5-methyl-2(3H)-furanone 
• 107-82-4 i-pentyl bromide 
• 627-98-5 5-methyl-1-hexanol 
• 818-58-6 methyl (E)-pent-3-enoate 
• 10266-05-4 1-iodo-5-methylhexane 
• 92694-51-4 (S)-(+)-β-angelica lactone 
• 768-33-2 phenyldimethylsilyl chloride 

Relevant articles and documents

Brief syntheses of (+)-blastmycinone and related γ-lactones from an asymmetrically dihydroxylated carboxylic ester

A method for synthesizing optically active trans,trans-configurated α,β,γ-substituted γ-lactones is presented. Asymmetric hydroxylation of ester 8 with AD mix α (AD mix β) and subsequent dehydration provided butenolide S-6 (R-6). Conjugate addition of Li2(Me2PhSi)2Cu(CN) to S-6 followed by alkylation of the resulting enolate led to the stereopure silyllactones 9-11. They furnished the title compounds after oxidative removal of the Me2PhSi group.