214603-19-7

Basic information

• Product Name: 2,3-dihydro-1-oxo-1H-inden-2-yl-4-methylbenzenesulfonate
• Synonyms: 2,3-dihydro-1-oxo-1H-inden-2-yl-4-methylbenzenesulfonate
• CAS NO: 214603-19-7
• Molecular Weight: 302.351
• Mol File: 214603-19-7.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2,3-dihydro-1-oxo-1H-inden-2-yl-4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-1-oxo-1H-inden-2-yl-4-methylbenzenesulfonate(214603-19-7)
• EPA Substance Registry System: 2,3-dihydro-1-oxo-1H-inden-2-yl-4-methylbenzenesulfonate(214603-19-7)

Safety Data

• Hazardous Substances Data: 214603-19-7(Hazardous Substances Data)

Upstream product

• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 83-33-0 inden-1-one 
• 19455-83-5 1H-inden-3-yl acetate 
• 104-15-4 toluene-4-sulfonic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 68253-35-0 (E)-indan-1-one oxime 
• 27126-76-7 [hydroxy(tosyloxy)iodo]benzene 
• 98503-39-0 indanone-⁽¹⁾-[O-(toluene-sulfonyl-⁽⁴⁾)-seqtrans-oxime ] 

Downstream Products

• 1391033-74-1 3-(p-tolyl)-10,10a-dihydroindeno[1,2-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 1340594-12-8 3-phenyl-10,10a-dihydroindeno[1,2-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 83-33-0 inden-1-one 
• 79465-06-8 trans-2-bromo-1-indanol 
• 67528-24-9 (1S,2S)-2-bromo-2,3-dihydro-1H-inden-1-ol 
• 768-22-9 (1S,2R)-epoxyindane 

Relevant articles and documents

Evolution of N-Heterocycle-Substituted Iodoarenes (NHIAs) to Efficient Organocatalysts in Iodine(I/III)-Mediated Oxidative Transformations

The reactivity of ortho-functionalized N-heterocycle-substituted iodoarenes (NHIAs) as organocatalysts in iodine(I/III)-mediated oxidations was systematically investigated in the α-tosyloxylation of ketones as the model reaction. During a systematic catalyst evolution, it was found that NH-triazoles and benzoxazoles have the most significant positive influence on the reactivity of the central iodine atom. A further catalyst improvement which focused on the substitution pattern of the arene revealed a remarkable ortho-effect. By introduction of an o-OMe group we were able to generate a novel NHIA with a so far unseen catalytic efficiency. This new catalyst is not only easy to synthesize but also enabled the α-tosyloxylation of carbonyl compounds at the lowest reported catalyst loading of only 1 mol%. Finally, the performance of this iodine(I) catalyst was successfully demonstrated in intramolecular oxidative couplings of biphenyls and oxidative rearrangements. (Figure presented.).

Novel α-tosyloxylation of ketones catalyzed by the in situ generated hypoiodous acid from alkyl iodide

Using a catalytic amount of 1-iodopropane, a novel and efficient procedure has been developed for direct preparation of α-tosyloxyketones from ketones. In this protocol, 1-iodopropane is first oxidized into iodosylpropane, which decomposes to form the key

A facile synthesis of novel dihydroindeno[1,2-e][1,2,4]triazolo[3,4-b][1,3, 4]thiadiazines using HTIB

The synthesis of a series of 21 novel 3-alkyl/aryl-7/9-methyl-10,10a- dihydroindeno[1,2-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazines (4) has been achieved by the cyclocondensation between 4/6-methyl-2-tosyloxy-1-indanones (2) and 3-alkyl/aryl-4-amino-5-mercapto-1,2,4-s-triazoles (3). 4/6-Methyl-2- tosyloxy-1-indanones (2) were readily accessible through hypervalent iodine oxidation of 4/6-methyl-1-indanones using [(hydroxy)tosyloxyiodo]benzene (HTIB, Koser's reagent) in acetonitrile.