21462-02-2

Basic information

• Product Name: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, methyl ester, (2Z)-
• CAS NO: 21462-02-2
• Molecular Formula: C17H15NO3
• Molecular Weight: 281.311
• Mol File: 21462-02-2.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, methyl ester, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, methyl ester, (2Z)-(21462-02-2)
• EPA Substance Registry System: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, methyl ester, (2Z)-(21462-02-2)

Safety Data

• Hazardous Substances Data: 21462-02-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 124-41-4 sodium methylate 
• 495-69-2 Hippuric Acid 
• 191725-33-4 methyl 2-(benzoylamido)-3-hydroxy-3-phenylpropionate 
• 1084941-10-5 Bz-Z-ΔPhe(β-I)-OMe 
• 1242683-34-6 Bz-E-ΔPhe(β-Br)-OMe 
• 101602-07-7 methyl (Z)-2-benzamido-3-bromo-3-phenylacrylate 
• 100-52-7 benzaldehyde 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 55-21-0 benzamide 
• 26348-47-0 (Z)-2-benzamidocinnamic acid 
• 26348-46-9 (Z)-ethyl 2-benzamido-3-phenylacrylate 

Downstream Products

• 1015478-57-5 C₁₇H₁₆⁽²⁾HNO₃ 
• 25755-94-6 methyl 2,5-diphenyloxazole-4-carboxylate 
• 1084941-10-5 Bz-Z-ΔPhe(β-I)-OMe 
• 1242683-34-6 Bz-E-ΔPhe(β-Br)-OMe 
• 101602-07-7 methyl (Z)-2-benzamido-3-bromo-3-phenylacrylate 
• 109597-21-9 α-(benzoyl-methyl-amino)-β-chloro-cinnamic acid 
• 103152-52-9 N-(3-chloro-1-oxo-inden-2-yl)-N-methyl-benzamide 
• 109448-25-1 α-(benzoyl-methyl-amino)-trans-cinnamic acid 
• 30020-55-4 1,3,4-Triphenylpyrazol-5-carbonsaeure-methylester 
• 139285-21-5 3-(2,6-Dichloro-phenyl)-4-phenyl-isoxazole-5-carboxylic acid methyl ester 
• 89141-16-2 (Z)-N-benzoyl-β-methyldidehydrophenylalanine methyl ester 
• 7510-56-7 4-phenyl-1H-pyrazole-3-carboxylic acid 

Relevant articles and documents

Cyclosophoraose as a catalytic carbohydrate for methanolysis

A novel catalytic methanolysis can be induced by a natural cyclooligosaccharide, a cyclosophoraose (cyclic-(1→2)-β-D-glucan, Cys), which is a member of a family of unbranched cyclooligosaccharides produced as intra- or extraoligosaccharides by soil microorganisms of the genus, Rhizobium. Cys catalyzed the methanolysis for 5(4H)-oxazolones and various phospholipids. Cys enhanced the methanolysis reaction about 9200-fold for a benzylidene oxazolone or 250-fold for dipalmitoylphosphatidylcholine comparing with control. In this study, we describe that natural cyclosophoraoses isolated from the Rhizobium species function as catalytic carbohydrates for the methanolysis.

Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates

Earth-abundant nickel, coordinated with a suitable chiral bisphosphine ligand, was found to be an efficient catalyst for the asymmetric hydrogenation of 2-amidoacrylates, affording the chiral α-amino acid esters in quantitative yields and excellent enantioselectivity (up to 96 % ee). The active catalyst component was studied by NMR and HRMS, which helped us to realize high catalytic efficiency on a gram scale with a low catalyst loading (S/C=2000). The hydrogenated products could be simply converted into chiral α-amino acids, β-amino alcohols, and their bioactive derivatives. Furthermore, the catalytic mechanism was investigated using deuterium-labeling experiments and computational calculations.

Reactivity of unsaturated 5(4H)-oxazolones with Hg(II) acetate: Synthesis of methyl N-benzoylamino-3-arylacrylates

An efficient and high-yield procedure to prepare methyl N-benzoylamino-3-arylacrylates from unsaturated (Z)-2-aryl-4-arylidene-5-(4H)- oxazolones and Hg(OAc)2 in methanol is described herein. The observed reactivity of mercury(II) acetate here