26348-47-0

Basic information

• Product Name: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, (2Z)-
• CAS NO: 26348-47-0
• Molecular Formula: C16H13NO3
• Molecular Weight: 267.284
• Mol File: 26348-47-0.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, (2Z)-(26348-47-0)
• EPA Substance Registry System: 2-Propenoic acid, 2-(benzoylamino)-3-phenyl-, (2Z)-(26348-47-0)

Safety Data

• Hazardous Substances Data: 26348-47-0(Hazardous Substances Data)

Usage

Also known as

(Z)-N-(3-carboxy-1-oxo-2-propen-1-yl)-D-phenylalanine
Belongs to the class of compounds known as phenylpropanoic acids
Used in the pharmaceutical industry for drug synthesis
Used in research applications as a chemical building block
Potential biological activity
Studied for its ability to inhibit certain enzymes and receptors in the body

Upstream product

• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 495-69-2 Hippuric Acid 
• 100-52-7 benzaldehyde 
• 150-78-7 1,4-dimethoxybezene 
• 60-29-7 diethyl ether 
• 101-84-8 diphenylether 
• 26348-46-9 (Z)-ethyl 2-benzamido-3-phenylacrylate 
• 27573-05-3 methyl ester of benzoylaminocinnamic acid 
• 42267-16-3 threo-DL-β-phenylserine ethyl ester hydrochloride 
• 64951-87-7 (2RS,3SR)-2-benzoylamino-3-hydroxy-3-phenyl-propionic acid ethyl ester 
• 57427-85-7 (E)-α-(benzamido)-cinnamic acid 
• 2566-22-5 N-benzoyl-L-phenylalanine 

Downstream Products

• 132649-36-6 2-benzoylamino-3-phenyl-3-chloroacrylic acid 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 79965-45-0 N-(N-benzoyldehydrophenylalanyl)-(S)-valine methyl ester 
• 75179-48-5 (S)-((Z)-2-Benzoylamino-3-phenyl-acryloylamino)-phenyl-acetic acid methyl ester 
• 2566-22-5 N-benzoyl-L-phenylalanine 
• 37002-52-1 N-benzoyl-D-phenylalanine 
• 2566-22-5 DL-N-benzoylphenylalanine 
• 2566-22-5 N-benzoyl-L-phenylalanine 
• 63-91-2 L-phenylalanine 
• 21462-02-2 methyl (Z)-2-benzoylamino-3-phenyl-2-propenoate 
• 88152-84-5 bis(diphenylphosphinomethyl)dioxolane rhodium(I)(C₆H₅CONHCCHC₆H₅CO₂) 
• 32089-78-4 ethyl 2-(benzoylamino)-3-(phenyl)acrylate 
• 1155-48-2 2-benzoylaminocinnamic acid 
• 79965-48-3 Bz-D-Phe-L-Val-OMe 

Relevant articles and documents

Synthesis of oxazoles from enamides via phenyliodine diacetate-mediated intramolecular oxidative cyclization

A group of functionalized oxazoles were synthesized in moderate to good yields from enamides via phenyliodine diacetate (PIDA)-mediated intramolecular cyclization. The main advantageous features of the present method include its broad substrate scope and the heavy-metal-free characteristic of the oxidative carbon-oxygen bond formation process.

Practical preparation of Z-α-(N-acetylamino)- and Z-α-(N-benzoylamino)-α,β-unsaturated acids

An efficient two-step synthetic procedure for the preparation of numerous variations of N-protected α,β-unsaturated α-amino acids and their corresponding esters from N-protected glycine and either aliphatic or aromatic aldehydes was developed. The reaction involved cyclization of the N-protected glycine into oxazolone, condensation with the aldehyde, and ring opening with a base. Copyright Taylor & Francis Group, LLC.

Synthesis of L-threo- and L-erythro-amino acids: novel probes for conformational analysis of peptide side chains

An efficient and convenient route for the preparation of L-threo- and L-erythro-amino acids 5 as probes for the conformational analysis of peptide side chains by NMR spectroscopy is described.Stereoselective incorporation of deuterium into the α,β-positions of amino acid 5 was accomplished by catalytic deuteration of dehydroamino acid derivatives 1 and 2 followed by a combination of enzymic optical resilution and the racemization at the 2-position.Using these doubly labelled amino acids, it was possible to obtain vicinal coupling constants between carbonyl carbon and prochiral β-protons, J(13C-1Hβ1) and J(13C1-1Hβ2), through 13C NMR spectroscopy alone.We also demonstrate the determination of the fractional populations of rotamers in respect of the Cα-Cβ bond of the amino acids using the measured coupling constants.