214758-90-4

Basic information

• Product Name: 4-(1-hydroxy-1-methyl-ethyl)benzyl amine
• Synonyms: 4-(1-hydroxy-1-methyl-ethyl)benzyl amine
• CAS NO: 214758-90-4
• Molecular Weight: 165.235
• Mol File: 214758-90-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 4-(1-hydroxy-1-methyl-ethyl)benzyl amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-hydroxy-1-methyl-ethyl)benzyl amine(214758-90-4)
• EPA Substance Registry System: 4-(1-hydroxy-1-methyl-ethyl)benzyl amine(214758-90-4)

Safety Data

• Hazardous Substances Data: 214758-90-4(Hazardous Substances Data)

Upstream product

• 3058-39-7 4-iodobenzonitrile 
• 77802-22-3 4-(2-hydroxypropan-2-yl)benzenecarbonitrile 
• 917-64-6 methyl magnesium iodide 
• 366-84-7 ethyl 4-(aminomethyl)benzoate 
• 1443-80-7 4-cyanophenyl methyl ketone 
• 13816-33-6 p-Cyanocumen 

Downstream Products

• 714975-80-1 (S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{(4R,6R)-3-[4-(1-hydroxy-1-methyl-ethyl)-benzyl]-4-methoxycarbonylmethyl-2-oxo-[1,3]oxazinan-6-yl}-ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester 
• 214758-10-8 2-(2,3-Dihydro-benzo(1,4)dioxin-6-yloxy)-N-(4-(1-Hydroxy-1-methyl-ethyl)-benzyl)-nicotinamide 
• 214757-94-5 N-(4-(1-Hydroxy-1-methyl-ethyl)-benzyl)-2-(3-methyl-benzo(d)isoxazol-7-yloxy)-nicotinamide 
• 214758-03-9 N-(4-(1-Hydroxy-1-methyl-ethyl)-benzyl)-2-(3-methyl-benzo(d)-isoxazol-5-yloxy)-nicotinamide 
• 214757-95-6 2-(3-Acetyl-5-chloro-phenoxy)-N-(4-(1-Hydroxy-1-methyl-ethyl)-benzyl)-nicotinamide 
• 214757-93-4 2-(3-Acetyl-4-chloro-phenoxy)-N-(4-(1-hydroxy-1-methyl-ethyl)-benzyl)-nicotinamide 

Relevant articles and documents

Scalable process for 4-(2-hydroxy-2-methyl)-ethyl-benzylamine

The preparation of the title compound has been revisited and improved. Starting from inexpensive cuminonitrile, 4-(2-hydroxy-2-methyl)-ethyl- benzylamine is obtained in a scalable two-step process with an overall yield of 55%. Copyright Taylor & Francis G

POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4

Disclosed herein are tricyclic compounds, including 3-(difluoromethyl)-4-methylpyrimido[4',5':4,5]thieno[2,3-c]pyridazin-8-amine compounds, which may be useful as positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR

POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4

Disclosed herein are thieno[2,3-b:5,4-c']dipyridin-8-amine and pyrido[4',3':4,5]thieno[2,3-c]pyridazin-8-amine compounds, which may be useful as positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4). A