21573-08-0 Usage
Description
2-amino-6-cyclopropylpyrimidin-4-ol is an organic compound with the molecular formula C7H11N3O. It is a derivative of pyrimidin-4-ol, featuring an amino group at the 2nd position and a cyclopropyl group at the 6th position. 2-amino-6-cyclopropylpyrimidin-4-ol is known for its potential applications in the pharmaceutical industry due to its unique structural properties.
Uses
Used in Pharmaceutical Industry:
2-amino-6-cyclopropylpyrimidin-4-ol is used as a reactant for the preparation of arylpyrimidines, which are known as 5-HT2B receptor antagonists. These antagonists play a crucial role in the treatment of various medical conditions, such as migraines, gastrointestinal disorders, and psychiatric disorders, by blocking the action of serotonin on the 5-HT2B receptor.
The compound's unique structure allows it to interact with the receptor site, providing a basis for the development of new drugs with improved efficacy and reduced side effects. Its use in the pharmaceutical industry is primarily focused on the synthesis of novel therapeutic agents targeting the 5-HT2B receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 21573-08-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,5,7 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 21573-08:
(7*2)+(6*1)+(5*5)+(4*7)+(3*3)+(2*0)+(1*8)=90
90 % 10 = 0
So 21573-08-0 is a valid CAS Registry Number.
21573-08-0Relevant articles and documents
SUBSTITUTED PYRAZOLOPYRIMIDINES AND SUBSTITUTED PURINES AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS
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Paragraph 0664, (2020/07/14)
The present disclosure provides compounds having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein X1, X2, X11, X12, R1, R3, R5, R5', R6, and R7 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to inhibit a USP1 protein and/or to treat a disorder responsive to the inhibition of USP1 proteins and USP1 activity. Compounds of the present disclosure are especially useful for treating cancer.
2 -AMINO-PYRIMIDINE DERIVATIVES AS HISTAMINE H4 ANTAGONISTS
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Page/Page column 58, (2009/07/03)
2-Aminopyrimidine derivatives of formula (I), wherein the meaning of the different substituents are those indicated in the description. These compounds are useful as histamine H4 receptor antagonists.
