21640-31-3

Basic information

• Product Name: 2-benzylisoquinoline-1,3(2H,4H)-dione
• Synonyms: 1,3(2H,4H)-isoquinolinedione, 2-(phenylmethyl)-; 2-Benzylisoquinoline-1,3(2H,4H)-dione
• CAS NO: 21640-31-3
• Molecular Formula: C₁₆H₁₃NO₂
• Molecular Weight: 251.2799
• Mol File: 21640-31-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 466.4°C at 760 mmHg
• Flash Point: 223.9°C
• Density: 1.265g/cm³
• Vapor Pressure: 7.1E-09mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: 2-benzylisoquinoline-1,3(2H,4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzylisoquinoline-1,3(2H,4H)-dione(21640-31-3)
• EPA Substance Registry System: 2-benzylisoquinoline-1,3(2H,4H)-dione(21640-31-3)

Safety Data

• Hazardous Substances Data: 21640-31-3(Hazardous Substances Data)

Upstream product

• 89-51-0 Homophthalic acid 
• 100-46-9 benzylamine 
• 703-59-3 homophthalic anhydride 
• 100-51-6 benzyl alcohol 

Downstream Products

• 104465-74-9 2-benzyl-4-<(ethoxycarbonyl)methyl>homophthalimide 
• 143370-34-7 4-(anilinomethylene)-2-benzyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione 
• 143370-33-6 2-benzyl-1,2,3,4-tetrahydro-4-(methoxymethylene)isoquinoline-1,3-dione 
• 21640-35-7 N-benzylisoquinoline-1,3,4(2H)-trione 
• 82342-55-0 N-benzoyl-homophthalimide 
• 59168-24-0 2-benzyl-3-hydroxy-3,4-dihydro-2H-isoquinolin-1-one 
• 190579-12-5 2-Benzyl-4-isopropyl-4H-isoquinoline-1,3-dione 
• 182871-00-7 4,4-Diallyl-2-benzyl-4H-isoquinoline-1,3-dione 

Relevant articles and documents

Iodine-catalyzed oxidative multiple C-H bond functionalization of isoquinolines with methylarenes: An efficient synthesis of isoquinoline-1,3,4(2: H)-triones

An iodine-catalyzed multiple C-H bond functionalization of isoquinolines with methylarenes via a successive benzylic sp3 C-H iodination/N-benzylation/amidation/double sp2 C-H oxidation sequence is developed. This reaction utilizes un

Enantioselective synthesis of isoquinoline-1,3(2: H,4 H)-dione derivatives via a chiral phosphoric acid catalyzed aza-Friedel-Crafts reaction

A highly enantioselective aza-Friedel-Crafts reaction of structurally new ketimines with indoles and pyrrole is developed by using a chiral phosphoric acid as the catalyst. This protocol enables the first enantioselective synthesis of isoquinoline-1,3(2H,

Flower-shaped ZnO nanoparticles as an efficient, heterogeneous and reusable catalyst in the synthesis of N-arylhomophthalimides and benzannelated isoquinolinones

A simple and green protocol, developed utilizing an efficient, heterogeneous and recyclable catalyst, i.e. zinc oxide nanoparticles (ZnO NPs)-mediated synthesis of N-arylhomophthalimides and benzannelated isoquinolinones, is reported. The structures of th