21645-99-8Relevant articles and documents
Improved synthesis of methyl 7,7-ethylenedioxy-3-methyl-9-oxobicyclo[3.3.1]non-3-ene-1-carboxylate, intermediate for the synthesis of Huperzine A analogues
Camps, Pelayo,Contreras, Joan,Font-Bardia, Merce,Solans, Xavier
, p. 9 - 18 (1996)
The title compound 4 has been obtained in an improved yield, from 1 via alcohol 2a, which was dehydrated by pyrolytic syn-elimination of its derived thiocarbonate 2c. A trans-configuration of 2a and its stereoisomer 3a was established by X-ray diffraction analysis of their mesylates 2b and 3b.