21709-70-6

Basic information

• Product Name: BENZAMIDE, N-(1-ACETYL-3-METHYLBUTYL)-
• Synonyms: BENZAMIDE, N-(1-ACETYL-3-METHYLBUTYL)-;N-(1-ACETYL-3-METHYLBUTYL) BENZAMIDE
• CAS NO: 21709-70-6
• Molecular Formula: C₁₄H₁₉NO₂
• Molecular Weight: 233.31
• Mol File: 21709-70-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BENZAMIDE, N-(1-ACETYL-3-METHYLBUTYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZAMIDE, N-(1-ACETYL-3-METHYLBUTYL)-(21709-70-6)
• EPA Substance Registry System: BENZAMIDE, N-(1-ACETYL-3-METHYLBUTYL)-(21709-70-6)

Safety Data

• Hazardous Substances Data: 21709-70-6(Hazardous Substances Data)

Upstream product

• 50996-03-7 benzamidoacetone 
• 513-36-0 isobutyryl chloride 
• 1466-83-7 N-benzoyl-DL-leucine 
• 917-54-4 methyllithium 

Downstream Products

• 5440-24-4 (+/-)-2-methyl-4-amino-5-hexanone hydrochloride 

Relevant articles and documents

Pyrrolomorphinans as δ opioid receptor antagonists. The role of steric hindrance in conferring selectivity

A series of 2',3'-disubstituted pyrrolomorphinans (5a-i) were synthesized to determine the role of steric hindrance at μ and γ receptors in promoting δ opioid receptor antagonist selectivity. In smooth muscle preparations, five members of the series (5a-c,e,f) possessed K(e) values in the range 2-15 nM and were 6 selective. Since the unsubstituted analogue 4 possessed δ antagonist potency of similar magnitude, but was not δ selective, it is suggested that the 2',3'substitution confers δ selectivity by hindering the interaction of the pharmacophore at μ and γ receptors, while not affecting δ receptors.