5440-24-4

Basic information

• Product Name: 3-amino-5-methyl-hexan-2-one
• Synonyms: 3-amino-5-methyl-hexan-2-one
• CAS NO: 5440-24-4
• Molecular Formula: C₇H₁₅NO*ClH
• Molecular Weight: 0
• Mol File: 5440-24-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 174.2°Cat760mmHg
• Flash Point: 59.2°C
• Appearance: /
• Density: 0.887g/cm³
• Vapor Pressure: 1.22mmHg at 25°C
• Refractive Index: 1.434
• CAS DataBase Reference: 3-amino-5-methyl-hexan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-5-methyl-hexan-2-one(5440-24-4)
• EPA Substance Registry System: 3-amino-5-methyl-hexan-2-one(5440-24-4)

Safety Data

• Hazardous Substances Data: 5440-24-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H15NO/c1-5(2)4-7(8)6(3)9/h5,7H,4,8H2,1-3H3

Upstream product

• 59303-00-3 5-methyl-hexane-2,3-dione-3-oxime 
• 30057-77-3 N-(5-methyl-2-oxohexan-3-yl)acetamide 
• 21709-70-6 (+/-)-3-benzamido-5-methyl-2-hexanone 
• 1466-83-7 N-benzoyl-DL-leucine 
• 110-12-3 5-Methyl-2-hexanone 
• 328-39-2 LEUCINE 

Downstream Products

• 107324-94-7 3-[3-(4-nitrophenoxy)propionylamino]-5-methyl-2-hexanone 

Relevant articles and documents

Pyrrolomorphinans as δ opioid receptor antagonists. The role of steric hindrance in conferring selectivity

A series of 2',3'-disubstituted pyrrolomorphinans (5a-i) were synthesized to determine the role of steric hindrance at μ and γ receptors in promoting δ opioid receptor antagonist selectivity. In smooth muscle preparations, five members of the series (5a-c,e,f) possessed K(e) values in the range 2-15 nM and were 6 selective. Since the unsubstituted analogue 4 possessed δ antagonist potency of similar magnitude, but was not δ selective, it is suggested that the 2',3'substitution confers δ selectivity by hindering the interaction of the pharmacophore at μ and γ receptors, while not affecting δ receptors.