21820-50-8

Basic information

• Product Name: Phenylalanine, hydrazide
• CAS NO: 21820-50-8
• Molecular Formula: C9H13N3O
• Molecular Weight: 179.222
• Mol File: 21820-50-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phenylalanine, hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylalanine, hydrazide(21820-50-8)
• EPA Substance Registry System: Phenylalanine, hydrazide(21820-50-8)

Safety Data

• Hazardous Substances Data: 21820-50-8(Hazardous Substances Data)

Upstream product

• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 7803-57-8 hydrazine hydrate 
• 63-91-2 L-phenylalanine 
• 1795-96-6 phenylalanine ethyl ester 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 15028-44-1 DL-phenylalanine methyl ester 

Downstream Products

• 21820-50-8 2-amino-3-phenylpropionic acid hydrazide 
• 121475-84-1 D-phenylalanine hydrazide 
• 1356072-81-5 N'-[(2E/Z)-4-nitrobenzylidene]-(2S)-amino-3-phenylpropanehydrazide 
• 1448820-14-1 1-[(1-ethoxyethylene)amino]-2-methyl-4-benzylimidazol-5(4H)-one 
• 143668-40-0 5-benzyl-3-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-6(5H)-one 
• 143668-41-1 5-benzyl-3-ethyl-1,4,5,6-tetrahydro-1,2,4-triazin-6(5H)-one 
• 1448820-15-2 1-[(1-ethoxypropylene)amino]-2-ethyl-4-benzylimidazol-5(4H)-one 
• 1448820-16-3 1-[(1-ethoxybenzylidene)amino]-2-phenyl-4-benzylimidazol-5(4H)-one 
• 63-91-2 L-phenylalanine 
• 1351400-23-1 2[(4-methoxybenzylidene)amino]-3-phenylpropinic acid (4-methoxybenzylidene)hydrazide 
• 142071-75-8 5-benzyl-2-methyl-3-(4-methoxybenzylidenamino)-1-imidazolin-4-one 
• 15150-71-7 5-benzyl-3-methyl-6-oxo-1,6-dihydro-1,2,4-triazine 
• 350984-52-0 5-(S)-benzyl-3-[(S)-1-[N-(tert-butoxycarbonyl)amino]-2-phenethyl]-4,5-dihydro-1,2,4-triazin-6-(1H)-one 

Relevant articles and documents

Chiral arylideneaminoimidazolidin-4-ones: Green synthesis and isomerisation mechanism in solution

A green and eco-friendly synthetic approach of pure 2,5-disubstituted 3-arylideneaminoimidazolidin-4-ones is developed using water as the solvent. These new chiral arylideneaminoimidazolidin-4-one derivatives were obtained diastereoselectively in high ove

Synthesis of novel 1-[(1-ethoxymethylene)amino]imidazol-5(4H)-ones and 1,2,4-triazin-6(5H)-ones from optically active α-aminocarboxylic acid hydrazides

New derivatives of 1-[(1-ethoxymethylene)amino]imidazol-5(4H)-one and 1,2,4-triazin-6(5H)-one were synthesized via reactions of optically active α-aminocarboxylic acid hydrazides and triethyl orthoesters in xylene. The factors influencing the formation of the unexpected five-membered products and attempts to elucidate the mechanism are discussed.

Synthesis and Antitubercular Activity of Novel Amino Acid Derivatives

In this work, 17 new N-acylhydrazone derivatives of amino acids have been evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv. The compounds 8b, 8e, 8f, 9a-d, and 10c exhibited an important minimum inhibitory concentration activity between 12.5 and 50μg/mL, which can be compared with that of the tuberculostatic drug d-cycloserine (20μg/mL). In this work 17 new N-acylhydrazone derivatives of amino acids have been evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv. Eight compounds were non-cytotoxic and exhibited an important MIC activity between 12.5 and 50μg/mL, which can be compared with that of the tuberculostatic drug d-cycloserine (20μg/mL).