21905-72-6 Usage
Description
2-(4-Methylphenoxy)benzoic acid methyl ester is an organic compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its aromatic structure and ester functional group, which contribute to its reactivity and potential applications in the chemical and pharmaceutical industries.
Uses
Used in Pharmaceutical Industry:
2-(4-Methylphenoxy)benzoic acid methyl ester is used as an intermediate in the synthesis of Balsalazide (B116300) related compounds. Balsalazide is a medication used to treat mild to moderate ulcerative colitis, a chronic inflammatory bowel disease. The ester's role in the synthesis process is crucial for the development of effective treatments for this condition.
Check Digit Verification of cas no
The CAS Registry Mumber 21905-72-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,0 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 21905-72:
(7*2)+(6*1)+(5*9)+(4*0)+(3*5)+(2*7)+(1*2)=96
96 % 10 = 6
So 21905-72-6 is a valid CAS Registry Number.
21905-72-6Relevant articles and documents
N-Heterocyclic carbene/photo-cocatalyzed oxidative Smiles rearrangement: Synthesis of aryl salicylates from: O -aryl salicylaldehydes
Xia, Zi-Hao,Dai, Lei,Gao, Zhong-Hua,Ye, Song
supporting information, p. 1525 - 1528 (2020/02/13)
The N-heterocyclic carbene/photo-cocatalyzed oxidative Smiles rearrangement of O-aryl salicylaldehydes was developed. Both electron-deficient and electron-rich aryls worked well as migrating groups, giving the corresponding aryl salicylates in good yields. This reaction features formation of two new C-O bonds and one C-O bond cleavage via metal-free oxidation of the Breslow intermediate using oxygen as the terminal oxidant and following the Smiles rearrangement under photocatalysis.
5-Substituted-2-furoic Acids as Latent Dienes for the Preparation of Aryl Ethers and Thioethers via the Diels-Alder Reaction
Cella, James A.
, p. 2099 - 2103 (2007/10/02)
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