30087-38-8Relevant articles and documents
ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES
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, (2008/06/13)
Substituted imidazoles such as STR1 are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.
Nonpeptide Angiotensin II Receptor Antagonist: N-imidazoles and Related Compounds as Potent Antihypertensives
Carini, David J.,Duncia, John V.,Johnson, Alexander L.,Chiu, Andrew T.,Price, William A.,et al.
, p. 1330 - 1336 (2007/10/02)
A series of compounds has been synthesized and demonstrated to be antagonists of the angiotensin II (AII) receptor.These compounds are structurally related to the N-(benzamidobenzyl)imidazoles and extend the scope of this new class of nonpeptide AII antag