21930-99-4

Basic information

• Product Name: Benzamide, N-[3-methyl-1-[(phenylamino)carbonyl]butyl]-, (S)-
• CAS NO: 21930-99-4
• Molecular Formula: C19H22N2O2
• Molecular Weight: 310.396
• Mol File: 21930-99-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[3-methyl-1-[(phenylamino)carbonyl]butyl]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[3-methyl-1-[(phenylamino)carbonyl]butyl]-, (S)-(21930-99-4)
• EPA Substance Registry System: Benzamide, N-[3-methyl-1-[(phenylamino)carbonyl]butyl]-, (S)-(21930-99-4)

Safety Data

• Hazardous Substances Data: 21930-99-4(Hazardous Substances Data)

Upstream product

• 1466-83-7 N-benzoyl-DL-leucine 
• 555-48-6 2-amino-N-phenyl-acetamide 
• 67392-64-7 N-(4-methyl-1-oxo-1-(phenylamino)pentan-2-yl)benzamide 
• 62-53-3 aniline 
• 2018-66-8 Z-Leu-OH 
• 2419-38-7 N-phthaloyl-(S)-leucine 
• 98-88-4 benzoyl chloride 
• 21931-02-2 (S)-benzyl 4-methyl-1-oxo-1-(phenylamino)pentan-2-ylcarbamate 
• 30816-20-7 N,N-phthaloyl-L-leucine anilide 
• 1466-83-7 N-benzoyl-L-leucine 

Relevant articles and documents

Synthesis of new C3 symmetric amino acid- and aminoalcohol-containing chiral stationary phases and application to HPLC enantioseparations

We recently reported a new C3-symmetric (R)-phenylglycinol N-1,3,5-benzenetricarboxylic acid-derived chiral high-performance liquid chromatography (HPLC) stationary phase (CSP 1) that demonstrated better results as compared to a previously described N-3,5-dintrobenzoyl (DNB) (R)-phenylglycinol-derived CSP. Over a decade ago, (S)-leucinol, (R)-phenylglycine, and (S)-leucine derivatives were used as the starting materials of 3,5-DNB-based Pirkle-type CSPs for chiral separation. In this study, three new C3-symmetric CSPs (CSP 2, 3, and 4) were prepared by combining the ideas and results mentioned above. Here we describe the synthetic procedures and applications of the new C3-symmetric CSPs (CSP 2–CSP 4).