219508-62-0 Usage
Description
1-Boc-6-aminoindole, also known as Aminoindole-1-carboxylic Acid tert-Butyl Ester, is a chemical compound that serves as a reagent in the synthesis of Syk and Abl inhibitors. It is a white to pale yellow solid with significant applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-Boc-6-aminoindole is used as a reagent for the synthesis of Syk and Abl inhibitors, which are important in the development of treatments for various diseases.
1-Boc-6-aminoindole is also used in the preparation of tyrosine kinase inhibitors, which play a crucial role in the treatment of cancer by targeting specific enzymes involved in cell growth and division.
Check Digit Verification of cas no
The CAS Registry Mumber 219508-62-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,5,0 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 219508-62:
(8*2)+(7*1)+(6*9)+(5*5)+(4*0)+(3*8)+(2*6)+(1*2)=140
140 % 10 = 0
So 219508-62-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2O2/c1-13(2,3)17-12(16)15-7-6-9-4-5-10(14)8-11(9)15/h4-8H,14H2,1-3H3
219508-62-0Relevant articles and documents
LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
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Paragraph 0741, (2017/04/28)
The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
