21970-65-0 Usage
Description
3-[benzyl(methyl)amino]-1-phenylpropan-1-one, also known as β-N-Benzyl-N''-methylaminopropiophenone, is an organic compound with a unique molecular structure that features a phenyl group, a propanone group, and a benzyl(methyl)amino functional group. 3-[benzyl(methyl)amino]-1-phenylpropan-1-one is known for its reactivity and utility in various chemical processes, particularly in the field of asymmetric hydrogenation.
Uses
Used in Pharmaceutical Industry:
3-[benzyl(methyl)amino]-1-phenylpropan-1-one is used as a reagent for asymmetric hydrogenation of amino ketones, which is a crucial step in the synthesis of various pharmaceutical compounds. The compound's ability to facilitate selective hydrogenation reactions contributes to the production of enantiomerically pure drugs, which are essential for ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Chemical Research:
In the field of chemical research, 3-[benzyl(methyl)amino]-1-phenylpropan-1-one serves as a valuable intermediate for the synthesis of complex organic molecules. Its unique structure allows for further functionalization and modification, making it a versatile building block for the development of new compounds with potential applications in various industries, including materials science, agrochemicals, and specialty chemicals.
Used in Asymmetric Catalysis:
3-[benzyl(methyl)amino]-1-phenylpropan-1-one is also used as a ligand in asymmetric catalysis, a field that focuses on the development of catalysts that can selectively produce one enantiomer of a chiral compound over the other. 3-[benzyl(methyl)amino]-1-phenylpropan-1-one's ability to enhance the selectivity of catalytic reactions is of great importance in the synthesis of enantiomerically pure compounds, which are often required for biological activity and pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 21970-65-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,7 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 21970-65:
(7*2)+(6*1)+(5*9)+(4*7)+(3*0)+(2*6)+(1*5)=110
110 % 10 = 0
So 21970-65-0 is a valid CAS Registry Number.
21970-65-0Relevant articles and documents
Novel carbon-carbon bond formation between N-methyl-3-phenyl-3- hydroxypropylamine and cresols catalyzed by p-toluenesulphonic acid
Gopalakrishnan,Sureshkumar,Kanagarajan,Thanusu,Govindan, Shanmugam,Reddy Ghanta, Mahesh
, p. 1923 - 1926 (2006)
The p-toluenesulphonic acid-catalyzed reaction between appropriate cresols and N-methyl-3-phenyl-3-hydroxypropylamine in refluxing toluene resulted in the formation of o -substituted phenol derivatives by an aromatic nucleophilic substitution reaction. Copyright Taylor & Francis Group, LLC.
PEG 400/cerium ammonium nitrate combined with microwave-assisted synthesis for rapid access to beta-amino ketones. an easy-to-use protocol for discovering new hit compounds
Rossino, Giacomo,Raimondi, Maria Valeria,Rui, Marta,Di Giacomo, Marcello,Rossi, Daniela,Collina, Simona
, (2018/04/06)
Compound libraries are important requirement in target-based drug discovery. In the present work, a small focused compound library based on β-aminoketone scaffold has been prepared combining microwave-assisted organic synthesis (MAOS) with polymer-assiste
Synthesis and antimicrobial activity of some new 1,2,4-triazine and benzimidazole derivatives
Bishnoi, Abha,Singh, Suruchi,Tiwari, Anil K.,Rani, Archna,Jain, Sapna,Tripathic
, p. 325 - 331 (2014/05/06)
1-(4-Substituted phenyl)-3-(substituted)propan-1-(1H-benzo[d]imidazol-2-yl) hydrazines and 1-(4-substituted phenyl)- 3-(substituted)propan-1-(5H-[1,2,4] triazino[5,6-b]indol-3-yl) hydrazines have been synthesized by the fusion of triazine and benzimidazole derivatives with Mannich bases. The synthesized compounds have been characterized and screened against ITCC 5226 Sclerotium rolfsii and ITCC 0482 Macrophomina phaseolina and MTCC739 Escherichia coli, ATCC6533 Bacillus subtilis, ATCC9144 Staphylococcus aureus, ATCC25619 Pseudomonas aeruginosa and ATCC24433 Candida albicans.
