22007-38-1

Basic information

• Product Name: Carbamothioic acid, (4-methoxyphenyl)-, O-ethyl ester
• CAS NO: 22007-38-1
• Molecular Formula: C10H13NO2S
• Molecular Weight: 211.285
• Mol File: 22007-38-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Carbamothioic acid, (4-methoxyphenyl)-, O-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamothioic acid, (4-methoxyphenyl)-, O-ethyl ester(22007-38-1)
• EPA Substance Registry System: Carbamothioic acid, (4-methoxyphenyl)-, O-ethyl ester(22007-38-1)

Safety Data

• Hazardous Substances Data: 22007-38-1(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 29336-07-0 N-(4-methoxyphenyl)-N’-(4-nitrophenyl)thiourea 
• 99358-06-2 S-nitrophenyl O-ethylxanthate 
• 15151-78-7 ethyl S-(4-chlorophenyl) thiolcarbonate 
• 19717-02-3 ethyl S-(4-methylphenyl) thiolcarbonate 
• 3278-38-4 S-phenyl O-ethylxanthate 
• 64-17-5 ethanol 
• 1227-45-8 1,3-bis-(p-methoxyphenyl)thiourea 
• 1219-96-1 N-(p-methoxyphenyl)-N'-phenylthiourea 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 

Downstream Products

• 7451-55-0 ethyl 4-methoxyphenylcarbamate 

Relevant articles and documents

Syntheses of N-alkyl, A,N-dialkyl, and N-(4-substituted phenyl) O-ethyl thioncarbamates: A kinetic study

The kinetics of the syntheses of N-alkyl, N,N-dialkyl, and N-(4-substituted phenyl) O-ethyl thioncarbamates from sodium ethyl xanthogenacetate, ten alkylamines, and eight substituted anilines were studied at 25, 30, 35, and 40 °C. The reactions were found to follow second-order kinetics. The kinetic (Arrhenius) parameters, such as the activation energy and the frequency factor, as well as the Eyring parameters, such as the standard entropy, the standard Gibbs energy, and the standard enthalpy of activation, were calculated from the second-order rate constants. The mechanism of the reaction was postulated based on the kinetic studies presented and the optimization of the reaction mechanism using the MOPAC PM6 semi-empirical method.

Ethanolysis of thioureas

In a study on the ethanolysis of thioureas it is demonstrated that N,N'-di- and trisubstituted aryl- and alkylarylthioureas when heated in ethanolic solution undergo fission to give N-arylthiocarbamic acid O-ethyl esters and amines. The reaction rates are depending on the nature of the substituents on the phenyl rings. Generally, the reactions are promoted by mineral acid.