220365-75-3Relevant articles and documents
A short efficient preparation of (+) and (-)-trans-2-phenylcyclohexanol
Carpenter, Bryon E.,Hunt, Ian R.,Keay, Brian A.
, p. 3107 - 3108 (1996)
Both enantiomers of trans-2-phenylcyclohexanol (1) (Whitesell's auxiliary) have been prepared in a facile three step sequence starting from phenylmagnesium bromide and cyclohexene oxide using Lipase PS30 to facilitate the resolution of the racemic alcohol
(S)-proline-derived catalysts for the acylative kinetic resolution of alcohols: A remote structural change allows a complete selectivity switch
Gleeson, Oliver,Gun'Ko, Yurii K.,Connon, Stephen J.
supporting information, p. 1728 - 1734 (2013/09/02)
A systematic preliminary study has identified a suite of catalysts, all readily prepared and derived from (S)-proline, which differ by a remote substituent only. If this substituent is capable of hydrogen-bond donation the catalyst will promote the resolu
Homobenzotetramisole: An effective catalyst for kinetic resolution of aryl-cycloalkanols
Birman, Vladimir B.,Li, Ximin
supporting information; experimental part, p. 1115 - 1118 (2009/04/07)
Homobenzotetramisole (HBTM), a ring-expanded analogue of the previously reported catalyst BTM, displays higher catalytic activity and a different structure-selectivity profile. It displays good enantioselectivities in kinetic resolution of secondary benzylic alcohols but is particularly effective for 2-aryl-substituted cycloalkanols.
