22098-10-8

Basic information

• Product Name: ETHYL (5-BROMOTHIEN-2-YL)GLYOXYLATE
• Synonyms: ETHYL (5-BROMOTHIEN-2-YL)GLYOXYLATE;ETHYL 2-(5-BROMO-2-THIENYL)-2-OXOACETATE;Ethyl (5-bromothien-2-yl)glyoxylate 97%;ETHYL 2-(5-BROMOTHIEN-2-YL)GLYOXYLATE;ethyl 2-(5-bromothiophen-2-yl)-2-oxoacetate;Ethyl (5-bromothien-2-yl)(oxo)acetate 97%;Ethyl (5-bromothien-2-yl)glyoxylate, 2-Bromo-5-[ethoxy(oxo)acetyl]thiophene;2-BroMo-5-[ethoxy(oxo)acetyl]thiophene
• CAS NO: 22098-10-8
• Molecular Formula: C₈H₇BrO₃S
• Molecular Weight: 263.11
• Mol File: 22098-10-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 70-72
• Boiling Point: 325 °C at 760 mmHg
• Flash Point: 150.3 °C
• Appearance: /
• Density: 1.612 g/cm³
• Vapor Pressure: 0.000237mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ETHYL (5-BROMOTHIEN-2-YL)GLYOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL (5-BROMOTHIEN-2-YL)GLYOXYLATE(22098-10-8)
• EPA Substance Registry System: ETHYL (5-BROMOTHIEN-2-YL)GLYOXYLATE(22098-10-8)

Safety Data

• Hazard Codes: Xi
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 22098-10-8(Hazardous Substances Data)

Usage

General Description

Ethyl (5-bromothien-2-yl)glyoxylate is a chemical compound with a unique structure composed of a thiophene ring, a bromine atom, an ethyl group, and a glyoxylate group. The thiophene entity, known for aromatic properties, provides stability to the compound. The bromine atom has the ability to participate in halogen bonding, which could be important in certain chemical reactions. The ethyl group is a common alkyl component in a variety of organic compounds, and the glyoxylate group contains both a carbonyl and a carboxyl group, which may lend the compound potential reactivity in certain chemical transformations. ETHYL (5-BROMOTHIEN-2-YL)GLYOXYLATE could be utilized in various chemical synthesis applications, due to its complex structural composition. However, specifics about its reactivity and potential uses are typically determined through experimental studies. As with all chemicals, adequate safety measures should be taken while handling Ethyl (5-bromothien-2-yl)glyoxylate.

InChI:InChI=1/C8H7BrO3S/c1-2-12-8(11)7(10)5-3-4-6(9)13-5/h3-4H,2H2,1H3

Upstream product

• 1003-09-4 2-bromothiophene 
• 4755-77-5 Ethyl oxalyl chloride 

Downstream Products

• 143365-53-1 ethyl α-phenyl-α-<2-(5-bromothienyl)>-α-hydroxyacetate 

Relevant articles and documents

Substituted cis-3,3,5-trimethylcyclohexyl thienylglycolates

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PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS

The present invention relates to compounds II useful as inhibitors of treating tuberculosis. The invention also provides processes for preparing compounds of the invention.

Synthesis and receptor affinities of new 3-quinuclidinyl α-heteroaryl-α- aryl-α-hydroxyacetates

Five analogues of 3-quinuclidinyl benzilate were prepared in which one phenyl ring was substituted by a heterocycle; a bromine was included on either the remaining phenyl or the heterocycle to provide information relating to the affinity of potential radiohalogenated derivatives. Their affinities for the muscarinic cholinergic receptor were determined. Replacing a phenyl ring with either the 2- or 3-furyl moiety or the 2- or 3-thienyl moiety did not significantly alter the affinity to the muscarinic receptor compared with 3-quinuclidinyl 4-bromobenzilate.