2211-61-2

Basic information

• Product Name: (1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone
• Synonyms: Methanone, (1-cyclohexyl-3-phenyl-2-aziridinyl)phenyl-, trans-
• CAS NO: 2211-61-2
• Molecular Formula: C₂₁H₂₃NO
• Molecular Weight: 305.4134
• Mol File: 2211-61-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 441.6°C at 760 mmHg
• Flash Point: 163.9°C
• Density: 1.149g/cm³
• Vapor Pressure: 5.38E-08mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: (1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone(2211-61-2)
• EPA Substance Registry System: (1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone(2211-61-2)

Safety Data

• Hazardous Substances Data: 2211-61-2(Hazardous Substances Data)

Usage

Description

(1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone, also known as CPAM, is a chemical compound with the molecular formula C20H21NO. It is a white solid that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. CPAM has been studied for its potential use in the treatment of various diseases, including cancer and infectious diseases. It is also known to have analgesic properties and has been investigated for its potential use as a pain reliever. Additionally, CPAM has been found to exhibit insecticidal activity, making it a potential candidate for use in pest control. Overall, CPAM is a versatile compound with potential applications in a variety of fields, including medicine and agriculture.

Uses

Used in Pharmaceutical Industry:
(1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone is used as an intermediate in the synthesis of pharmaceuticals for its potential use in the treatment of various diseases, including cancer and infectious diseases.
Used in Agrochemical Industry:
(1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone is used as an intermediate in the synthesis of agrochemicals for its potential use in pest control due to its insecticidal activity.
Used in Pain Management:
(1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone is used as a potential pain reliever for its analgesic properties.
Used in Drug Development:
(1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone is used in the development of new drugs for its potential therapeutic applications in medicine.

Upstream product

• 32147-20-9 (Z)-2-bromo-1,3-diphenylprop-2-en-1-one 
• 108-91-8 cyclohexylamine 
• 611-91-6 trans-2,3-dibromo-1,3-diphenylpropan-1-one 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 611-91-6 2,3-dibromo-1,3-diphenylpropane-1-one 

Downstream Products

• 97157-29-4 (+/-)-cyclohexyl-(1,3,5t-triphenyl-4,5-dihydro-1H-pyrazol-4r-yl)-amine 
• 21364-53-4 [3-cyclohexyl-5-((E)-1,2-diphenyl-vinyl)-2-phenyl-2,3-dihydro-oxazol-4-yl]-phenyl-methanone 
• 95797-23-2 cis-3-cyclohexyl-4-benzoyl-5-phenyl-1,3-imidazolidin-2-one 
• 95797-19-6 cis-2-chlorosulfonylimino-3-cyclohexyl-4-benzoyl-5-phenyl-1,3-oxazolidine 
• 102614-79-9 C₂₁H₂₃NO 
• 91671-43-1 1-cyclohexyl-2-(1-hydroxy-1-phenylpentyl)-3-phenylaziridine 
• 50743-12-9 1-cyclohexyl-2-phenyl-pyrrole-3,4-dicarboxylic acid dimethyl ester 
• 13803-64-0 2-benzoyl-1-cyclohexyl-5-phenyl-pyrrole-3,4-dicarboxylic acid dimethyl ester 
• 26362-42-5 t-4-benzoyl-3-cyclohexyl-c-5-(4-nitrophenyl)-r-2-phenyloxazolidine 
• 25674-67-3 2-benzoyl naphtho<1,2-d>oxazole 
• 3574-02-5 2-phenylnaphtho[1,2-d]oxazole 

Relevant articles and documents

I2/TBHP mediated diastereoselective synthesis of spiroaziridines

Eventhough spiroheterocycles are considered as emerging drug candidates, synthesis of spiroaziridines has not been well explored so far. Herein, we disclose an efficient I2/TBHP mediated diastereoselective synthesis of N-alkyl spiroaziridines from primary amines and easily accessible α,β-unsaturated ketones. The reaction is also compatible for the synthesis of 2-aroylaziridines.