221341-06-6

Basic information

• Product Name: (S)-3-{2-[3-(4-{Amino-[(E)-tert-butoxycarbonylimino]-methyl}-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-2-(bis-allyloxy-phosphorylamino)-propionic acid methyl ester
• CAS NO: 221341-06-6
• Molecular Weight: 607.601
• Mol File: 221341-06-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-{2-[3-(4-{Amino-[(E)-tert-butoxycarbonylimino]-methyl}-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-2-(bis-allyloxy-phosphorylamino)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-{2-[3-(4-{Amino-[(E)-tert-butoxycarbonylimino]-methyl}-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-2-(bis-allyloxy-phosphorylamino)-propionic acid methyl ester(221341-06-6)
• EPA Substance Registry System: (S)-3-{2-[3-(4-{Amino-[(E)-tert-butoxycarbonylimino]-methyl}-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-2-(bis-allyloxy-phosphorylamino)-propionic acid methyl ester(221341-06-6)

Safety Data

• Hazardous Substances Data: 221341-06-6(Hazardous Substances Data)

Upstream product

• 102-84-1 triallyl phosphite 
• 190446-44-7 methyl 3-[({3-[4-({[(1,1-dimethylethoxy)carbonyl]amino}iminomethyl)phenyl]-4,5-dihydro-5-isoxazolyl}acetyl)amino]-N-[(phenylmethoxy)carbonyl]-L-alanine 

Relevant articles and documents

Isoxazoline GPIIb/IIIa antagonists bearing a phosphoramidate

Isoxazolinylacetamides bearing a phosphoramidate group α- to the carboxylate moiety (3) were prepared and evaluated for in vitro antiplatelet efficacy. They were found to bind GPIIb/IIIa with high affinity and were potent antagonists of ADP mediated platelet aggregation.