2217-15-4 Usage
Description
(+)-Diisopropyl L-tartrate is a colorless to light yellow liquid that serves as a crucial reagent in the field of organic chemistry. It is widely utilized for the kinetic resolution of racemic allylic alcohols and α-furfuryl amides through enantioselective epoxidation, which is a process that selectively reacts with one enantiomer of a chiral molecule, leading to the formation of a specific product with a desired stereochemistry.
Uses
Used in Pharmaceutical Industry:
(+)-Diisopropyl L-tartrate is used as a reagent for the kinetic resolution of racemic allylic alcohols and α-furfuryl amides by enantioselective epoxidation. This application is significant in the pharmaceutical industry because it allows for the production of enantiomerically pure compounds, which are essential for the development of effective and safe drugs. Many drugs exhibit different pharmacological activities depending on their stereochemistry, and the use of (+)-Diisopropyl L-tartrate ensures that the desired enantiomer is obtained, leading to more targeted and potent therapeutic effects.
Used in Chemical Synthesis:
In the field of chemical synthesis, (+)-Diisopropyl L-tartrate is employed as a reagent for enantioselective epoxidation, which is a crucial reaction in the synthesis of various chiral compounds. This selective process allows chemists to obtain specific enantiomers with high purity, which is vital for the development of new materials, catalysts, and other specialty chemicals.
Used in Research and Development:
(+)-Diisopropyl L-tartrate is also used in research and development laboratories, where it is employed as a tool to study the stereochemistry of various organic compounds. The ability to selectively react with one enantiomer provides valuable insights into the structure and properties of chiral molecules, which can be applied to the design and synthesis of new compounds with specific biological activities or material properties.
Check Digit Verification of cas no
The CAS Registry Mumber 2217-15-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,1 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2217-15:
(6*2)+(5*2)+(4*1)+(3*7)+(2*1)+(1*5)=54
54 % 10 = 4
So 2217-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H18O6/c1-5(2)15-9(13)7(11)8(12)10(14)16-6(3)4/h5-8,11-12H,1-4H3/t7-,8-/m1/s1
2217-15-4Relevant articles and documents
Asymmetric Mannich-type synthesis of N-phosphinyl α-aminophosphonic acid monoesters
Fang, Zhijia,Yang, Haohao,Miao, Zhiwei,Chen, Ruyu
, p. 1586 - 1593 (2011)
A convenient diastereoselective synthesis of diisopropyl (2R,3R)-3-{{{(R/S)-aryl[(diethoxyphosphinyl)amino]methyl}hydroxyphosphinyl}oxy} -2-hydroxybutanedioate through Mannich-type reactions is reported. The reactions take place under mild conditions in good yields, and this makes it possible to introduce various substituents at the α-position to the P-atom of α-aminophosphonates. The chiral diisopropyl (4R,5R)-2-chloro-1,3,2- dioxaphospholane-4,5-dicarboxylate (3) was found to be a good phosphonylating agent in this stereoselective reaction. Copyright
A Simple and Efficient Procedure for Transesterification Catalyzed by Indium Triiodide
Ranu, Brindaban C.,Dutta, Pinak,Sarkar, Arunkanti
, p. 6027 - 6028 (2007/10/03)
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